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The structural basis of promiscuity in small multidrug resistance transporters.
Nat Commun. 2020 Nov 27;11(1):6064. doi: 10.1038/s41467-020-19820-8.
Nat Commun. 2020.
PMID: 33247110
Free PMC article.
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis.
Garnish SE, Meng Y, Koide A, Sandow JJ, Denbaum E, Jacobsen AV, Yeung W, Samson AL, Horne CR, Fitzgibbon C, Young SN, Smith PPC, Webb AI, Petrie EJ, Hildebrand JM, Kannan N, Czabotar PE, Koide S, Murphy JM.
Garnish SE, et al. Among authors: denbaum e.
Nat Commun. 2021 Apr 13;12(1):2211. doi: 10.1038/s41467-021-22400-z.
Nat Commun. 2021.
PMID: 33850121
Free PMC article.
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Monobody adapter for functional antibody display on nanoparticles for adaptable targeted delivery applications.
Albert C, Bracaglia L, Koide A, DiRito J, Lysyy T, Harkins L, Edwards C, Richfield O, Grundler J, Zhou K, Denbaum E, Ketavarapu G, Hattori T, Perincheri S, Langford J, Feizi A, Haakinson D, Hosgood SA, Nicholson ML, Pober JS, Saltzman WM, Koide S, Tietjen GT.
Albert C, et al. Among authors: denbaum e.
Nat Commun. 2022 Oct 11;13(1):5998. doi: 10.1038/s41467-022-33490-8.
Nat Commun. 2022.
PMID: 36220817
Free PMC article.
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Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies.
Petrie EJ, Birkinshaw RW, Koide A, Denbaum E, Hildebrand JM, Garnish SE, Davies KA, Sandow JJ, Samson AL, Gavin X, Fitzgibbon C, Young SN, Hennessy PJ, Smith PPC, Webb AI, Czabotar PE, Koide S, Murphy JM.
Petrie EJ, et al. Among authors: denbaum e.
Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8468-8475. doi: 10.1073/pnas.1919960117. Epub 2020 Mar 31.
Proc Natl Acad Sci U S A. 2020.
PMID: 32234780
Free PMC article.
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Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants.
Khan I, Koide A, Zuberi M, Ketavarapu G, Denbaum E, Teng KW, Rhett JM, Spencer-Smith R, Hobbs GA, Camp ER, Koide S, O'Bryan JP.
Khan I, et al. Among authors: denbaum e.
Cell Rep. 2022 Feb 8;38(6):110322. doi: 10.1016/j.celrep.2022.110322.
Cell Rep. 2022.
PMID: 35139380
Free PMC article.
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Targeting the KRAS α4-α5 allosteric interface inhibits pancreatic cancer tumorigenesis.
Khan I, Marelia-Bennet C, Lefler J, Zuberi M, Denbaum E, Koide A, Connor DM, Broome AM, Pécot T, Timmers C, Ostrowski MC, Koide S, O'Bryan JP.
Khan I, et al. Among authors: denbaum e.
Small GTPases. 2022 Jan;13(1):114-127. doi: 10.1080/21541248.2021.1906621. Epub 2021 May 5.
Small GTPases. 2022.
PMID: 33949915
Free PMC article.
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