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Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis.
Bettermann K, Mehta AK, Hofer EM, Wohlrab C, Golob-Schwarzl N, Svendova V, Schimek MG, Stumptner C, Thüringer A, Speicher MR, Lackner C, Zatloukal K, Denk H, Haybaeck J. Bettermann K, et al. Among authors: denk h. Oncotarget. 2016 Nov 8;7(45):73309-73322. doi: 10.18632/oncotarget.12325. Oncotarget. 2016. PMID: 27689336 Free PMC article.
Hepatocellular carcinomas with intracellular hyaline bodies have a poor prognosis.
Aigelsreiter A, Neumann J, Pichler M, Halasz J, Zatloukal K, Berghold A, Douschan P, Rainer F, Stauber R, Haybaeck J, Denk H, Lackner C. Aigelsreiter A, et al. Among authors: denk h. Liver Int. 2017 Apr;37(4):600-610. doi: 10.1111/liv.13325. Epub 2017 Jan 12. Liver Int. 2017. PMID: 27885796
BACKGROUND & AIMS: Mallory-Denk bodies (MDBs) and intracellular hyaline bodies (IHBs) are cytoplasmic inclusions found in a subset of hepatocellular carcinoma (HCC). ...The prognostic impact of inclusions was assessed using Kaplan-Meier and multivariate Cox proportiona …
BACKGROUND & AIMS: Mallory-Denk bodies (MDBs) and intracellular hyaline bodies (IHBs) are cytoplasmic inclusions found in a subse …
Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.
Fickert P, Krones E, Pollheimer MJ, Thueringer A, Moustafa T, Silbert D, Halilbasic E, Yang M, Jaeschke H, Stokman G, Wells RG, Eller K, Rosenkranz AR, Eggertsen G, Wagner CA, Langner C, Denk H, Trauner M. Fickert P, et al. Among authors: denk h. Hepatology. 2013 Dec;58(6):2056-69. doi: 10.1002/hep.26599. Epub 2013 Oct 15. Hepatology. 2013. PMID: 23813550
Differential effects of norUDCA and UDCA in obstructive cholestasis in mice.
Fickert P, Pollheimer MJ, Silbert D, Moustafa T, Halilbasic E, Krones E, Durchschein F, Thüringer A, Zollner G, Denk H, Trauner M. Fickert P, et al. Among authors: denk h. J Hepatol. 2013 Jun;58(6):1201-8. doi: 10.1016/j.jhep.2013.01.026. Epub 2013 Jan 29. J Hepatol. 2013. PMID: 23369794 Free PMC article.
Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
Halilbasic E, Fiorotto R, Fickert P, Marschall HU, Moustafa T, Spirli C, Fuchsbichler A, Gumhold J, Silbert D, Zatloukal K, Langner C, Maitra U, Denk H, Hofmann AF, Strazzabosco M, Trauner M. Halilbasic E, et al. Among authors: denk h. Hepatology. 2009 Jun;49(6):1972-81. doi: 10.1002/hep.22891. Hepatology. 2009. PMID: 19475687 Free PMC article.
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