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15 results
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Oncogenic signaling of class I PI3K isoforms.
Denley A, Kang S, Karst U, Vogt PK. Denley A, et al. Oncogene. 2008 Apr 17;27(18):2561-74. doi: 10.1038/sj.onc.1210918. Epub 2007 Nov 12. Oncogene. 2008. PMID: 17998941
Phosphatidylinositol 3-kinase: the oncoprotein.
Vogt PK, Hart JR, Gymnopoulos M, Jiang H, Kang S, Bader AG, Zhao L, Denley A. Vogt PK, et al. Among authors: denley a. Curr Top Microbiol Immunol. 2010;347:79-104. doi: 10.1007/82_2010_80. Curr Top Microbiol Immunol. 2010. PMID: 20582532 Free PMC article. Review.
Requirement of phosphatidylinositol(3,4,5)trisphosphate in phosphatidylinositol 3-kinase-induced oncogenic transformation.
Denley A, Gymnopoulos M, Kang S, Mitchell C, Vogt PK. Denley A, et al. Mol Cancer Res. 2009 Jul;7(7):1132-8. doi: 10.1158/1541-7786.MCR-09-0068. Epub 2009 Jul 7. Mol Cancer Res. 2009. PMID: 19584261 Free PMC article.
Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase.
Kang S, Denley A, Vanhaesebroeck B, Vogt PK. Kang S, et al. Among authors: denley a. Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1289-94. doi: 10.1073/pnas.0510772103. Epub 2006 Jan 23. Proc Natl Acad Sci U S A. 2006. PMID: 16432180 Free PMC article.
Biochemical and biological characterization of tumor-associated mutations of p110alpha.
Denley A, Gymnopoulos M, Hart JR, Jiang H, Zhao L, Vogt PK. Denley A, et al. Methods Enzymol. 2008;438:291-305. doi: 10.1016/S0076-6879(07)38020-8. Methods Enzymol. 2008. PMID: 18413256
Structural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: correlation with effects on growth and development.
Denley A, Wang CC, McNeil KA, Walenkamp MJ, van Duyvenvoorde H, Wit JM, Wallace JC, Norton RS, Karperien M, Forbes BE. Denley A, et al. Mol Endocrinol. 2005 Mar;19(3):711-21. doi: 10.1210/me.2004-0409. Epub 2004 Dec 2. Mol Endocrinol. 2005. PMID: 15576456
Differential activation of insulin receptor isoforms by insulin-like growth factors is determined by the C domain.
Denley A, Brierley GV, Carroll JM, Lindenberg A, Booker GW, Cosgrove LJ, Wallace JC, Forbes BE, Roberts CT Jr. Denley A, et al. Endocrinology. 2006 Feb;147(2):1029-36. doi: 10.1210/en.2005-0736. Epub 2005 Oct 20. Endocrinology. 2006. PMID: 16239300
Molecular interactions of the IGF system.
Denley A, Cosgrove LJ, Booker GW, Wallace JC, Forbes BE. Denley A, et al. Cytokine Growth Factor Rev. 2005 Aug-Oct;16(4-5):421-39. doi: 10.1016/j.cytogfr.2005.04.004. Cytokine Growth Factor Rev. 2005. PMID: 15936977 Review.
Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR.
Denley A, Bonython ER, Booker GW, Cosgrove LJ, Forbes BE, Ward CW, Wallace JC. Denley A, et al. Mol Endocrinol. 2004 Oct;18(10):2502-12. doi: 10.1210/me.2004-0183. Epub 2004 Jun 17. Mol Endocrinol. 2004. PMID: 15205474
Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.
Denley A, Carroll JM, Brierley GV, Cosgrove L, Wallace J, Forbes B, Roberts CT Jr. Denley A, et al. Mol Cell Biol. 2007 May;27(10):3569-77. doi: 10.1128/MCB.01447-06. Epub 2007 Feb 26. Mol Cell Biol. 2007. PMID: 17325037 Free PMC article.
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