Dennis PA - Search Results

1

Perifosine: update on a novel Akt inhibitor.

Gills JJ, Dennis PA. Gills JJ, et al. Among authors: dennis pa. Curr Oncol Rep. 2009 Mar;11(2):102-10. doi: 10.1007/s11912-009-0016-4. Curr Oncol Rep. 2009. PMID: 19216841 Free PMC article. Review.

2

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation.

Brognard J, Clark AS, Ni Y, Dennis PA. Brognard J, et al. Among authors: dennis pa. Cancer Res. 2001 May 15;61(10):3986-97. Cancer Res. 2001. PMID: 11358816

3

Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2.

Cuello M, Ettenberg SA, Clark AS, Keane MM, Posner RH, Nau MM, Dennis PA, Lipkowitz S. Cuello M, et al. Among authors: dennis pa. Cancer Res. 2001 Jun 15;61(12):4892-900. Cancer Res. 2001. PMID: 11406568

4

Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants.

Brognard J, Dennis PA. Brognard J, et al. Among authors: dennis pa. Cell Death Differ. 2002 Sep;9(9):893-904. doi: 10.1038/sj.cdd.4401054. Cell Death Differ. 2002. PMID: 12181740

5

Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells.

Clark AS, West K, Streicher S, Dennis PA. Clark AS, et al. Among authors: dennis pa. Mol Cancer Ther. 2002 Jul;1(9):707-17. Mol Cancer Ther. 2002. PMID: 12479367

6

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells.

West KA, Brognard J, Clark AS, Linnoila IR, Yang X, Swain SM, Harris C, Belinsky S, Dennis PA. West KA, et al. Among authors: dennis pa. J Clin Invest. 2003 Jan;111(1):81-90. doi: 10.1172/JCI16147. J Clin Invest. 2003. PMID: 12511591 Free PMC article.

7

Activation of the PI3K/Akt pathway and chemotherapeutic resistance.

West KA, Castillo SS, Dennis PA. West KA, et al. Among authors: dennis pa. Drug Resist Updat. 2002 Dec;5(6):234-48. doi: 10.1016/s1368-7646(02)00120-6. Drug Resist Updat. 2002. PMID: 12531180 Review.

8

Altered protein kinase C (PKC) isoforms in non-small cell lung cancer cells: PKCdelta promotes cellular survival and chemotherapeutic resistance.

Clark AS, West KA, Blumberg PM, Dennis PA. Clark AS, et al. Among authors: dennis pa. Cancer Res. 2003 Feb 15;63(4):780-6. Cancer Res. 2003. PMID: 12591726

9

Modulating protein kinase C (PKC) to increase the efficacy of chemotherapy: stepping into darkness.

Lorenzo PS, Dennis PA. Lorenzo PS, et al. Among authors: dennis pa. Drug Resist Updat. 2003 Dec;6(6):329-39. doi: 10.1016/j.drup.2003.10.003. Drug Resist Updat. 2003. PMID: 14744497 Review.

10

Tobacco carcinogen-induced cellular transformation increases activation of the phosphatidylinositol 3'-kinase/Akt pathway in vitro and in vivo.

West KA, Linnoila IR, Belinsky SA, Harris CC, Dennis PA. West KA, et al. Among authors: dennis pa. Cancer Res. 2004 Jan 15;64(2):446-51. doi: 10.1158/0008-5472.can-03-3241. Cancer Res. 2004. PMID: 14744754

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