Denu JM - Search Results

1

Kinetic and Structural Basis for Acyl-Group Selectivity and NAD(+) Dependence in Sirtuin-Catalyzed Deacylation.

Feldman JL, Dittenhafer-Reed KE, Kudo N, Thelen JN, Ito A, Yoshida M, Denu JM. Feldman JL, et al. Among authors: denu jm. Biochemistry. 2015 May 19;54(19):3037-3050. doi: 10.1021/acs.biochem.5b00150. Epub 2015 May 4. Biochemistry. 2015. PMID: 25897714 Free PMC article.

2

Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis.

Hengge AC, Denu JM, Dixon JE. Hengge AC, et al. Among authors: denu jm. Biochemistry. 1996 Jun 4;35(22):7084-92. doi: 10.1021/bi960255i. Biochemistry. 1996. PMID: 8679534

3

Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases.

Borra MT, Langer MR, Slama JT, Denu JM. Borra MT, et al. Among authors: denu jm. Biochemistry. 2004 Aug 3;43(30):9877-87. doi: 10.1021/bi049592e. Biochemistry. 2004. PMID: 15274642

4

Vitamin B3 and sirtuin function.

Denu JM. Denu JM. Trends Biochem Sci. 2005 Sep;30(9):479-83. doi: 10.1016/j.tibs.2005.07.004. Trends Biochem Sci. 2005. PMID: 16039130 Review.

5

Small molecule regulation of Sir2 protein deacetylases.

Grubisha O, Smith BC, Denu JM. Grubisha O, et al. Among authors: denu jm. FEBS J. 2005 Sep;272(18):4607-16. doi: 10.1111/j.1742-4658.2005.04862.x. FEBS J. 2005. PMID: 16156783 Free article. Review.

6

SIRT1 top 40 hits: use of one-bead, one-compound acetyl-peptide libraries and quantum dots to probe deacetylase specificity.

Garske AL, Denu JM. Garske AL, et al. Among authors: denu jm. Biochemistry. 2006 Jan 10;45(1):94-101. doi: 10.1021/bi052015l. Biochemistry. 2006. PMID: 16388584 Free PMC article.

7

Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.

Smith BC, Denu JM. Smith BC, et al. Among authors: denu jm. Biochemistry. 2006 Jan 10;45(1):272-82. doi: 10.1021/bi052014t. Biochemistry. 2006. PMID: 16388603 Free PMC article.

8

Catalytic mechanism of a MYST family histone acetyltransferase.

Berndsen CE, Albaugh BN, Tan S, Denu JM. Berndsen CE, et al. Among authors: denu jm. Biochemistry. 2007 Jan 23;46(3):623-9. doi: 10.1021/bi602513x. Biochemistry. 2007. PMID: 17223684 Free PMC article.

9

Nucleosome recognition by the Piccolo NuA4 histone acetyltransferase complex.

Berndsen CE, Selleck W, McBryant SJ, Hansen JC, Tan S, Denu JM. Berndsen CE, et al. Among authors: denu jm. Biochemistry. 2007 Feb 27;46(8):2091-9. doi: 10.1021/bi602366n. Epub 2007 Feb 3. Biochemistry. 2007. PMID: 17274630 Free PMC article.

10

Sir2 deacetylases exhibit nucleophilic participation of acetyl-lysine in NAD+ cleavage.

Smith BC, Denu JM. Smith BC, et al. Among authors: denu jm. J Am Chem Soc. 2007 May 9;129(18):5802-3. doi: 10.1021/ja070162w. Epub 2007 Apr 17. J Am Chem Soc. 2007. PMID: 17439123 Free PMC article.

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