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Targeting inflammatory pathways for tumor radiosensitization.
Deorukhkar A, Krishnan S. Deorukhkar A, et al. Biochem Pharmacol. 2010 Dec 15;80(12):1904-14. doi: 10.1016/j.bcp.2010.06.039. Epub 2010 Jun 30. Biochem Pharmacol. 2010. PMID: 20599771 Free PMC article. Review.
Modulation of in vivo tumor radiation response via gold nanoshell-mediated vascular-focused hyperthermia: characterizing an integrated antihypoxic and localized vascular disrupting targeting strategy.
Diagaradjane P, Shetty A, Wang JC, Elliott AM, Schwartz J, Shentu S, Park HC, Deorukhkar A, Stafford RJ, Cho SH, Tunnell JW, Hazle JD, Krishnan S. Diagaradjane P, et al. Among authors: deorukhkar a. Nano Lett. 2008 May;8(5):1492-500. doi: 10.1021/nl080496z. Epub 2008 Apr 16. Nano Lett. 2008. PMID: 18412402 Free PMC article.
A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo.
Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Foxton C, Boakes A, Farooq M, Maru D, Diagaradjane P, Matsuo Y, Sinnett-Smith J, Gelovani J, Krishnan S, Aggarwal BB, Rozengurt E, Ireson CR, Guha S. Harikumar KB, et al. Among authors: deorukhkar a. Mol Cancer Ther. 2010 May;9(5):1136-46. doi: 10.1158/1535-7163.MCT-09-1145. Epub 2010 May 4. Mol Cancer Ther. 2010. PMID: 20442301 Free PMC article.
{Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.
Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, Koca C, Yadav VR, Tong Z, Gelovani JG, Guha S, Krishnan S, Aggarwal BB. Kunnumakkara AB, et al. Among authors: deorukhkar a. Cancer Res. 2010 Nov 1;70(21):8695-705. doi: 10.1158/0008-5472.CAN-10-2318. Epub 2010 Sep 23. Cancer Res. 2010. PMID: 20864511 Free PMC article.
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