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Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins.
Gerets HH, Tilmant K, Gerin B, Chanteux H, Depelchin BO, Dhalluin S, Atienzar FA. Gerets HH, et al. Among authors: depelchin bo. Cell Biol Toxicol. 2012 Apr;28(2):69-87. doi: 10.1007/s10565-011-9208-4. Epub 2012 Jan 19. Cell Biol Toxicol. 2012. PMID: 22258563 Free PMC article.
PEGylated Biopharmaceuticals: Current Experience and Considerations for Nonclinical Development.
Ivens IA, Achanzar W, Baumann A, Brändli-Baiocco A, Cavagnaro J, Dempster M, Depelchin BO, Rovira AR, Dill-Morton L, Lane JH, Reipert BM, Salcedo T, Schweighardt B, Tsuruda LS, Turecek PL, Sims J. Ivens IA, et al. Among authors: depelchin bo. Toxicol Pathol. 2015 Oct;43(7):959-83. doi: 10.1177/0192623315591171. Epub 2015 Aug 3. Toxicol Pathol. 2015. PMID: 26239651 Review.
Cardiac safety of lacosamide: the non-clinical perspective.
Delaunois A, Colomar A, Depelchin BO, Cornet M. Delaunois A, et al. Among authors: depelchin bo. Acta Neurol Scand. 2015 Nov;132(5):337-45. doi: 10.1111/ane.12413. Epub 2015 Apr 21. Acta Neurol Scand. 2015. PMID: 25903789