Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2011 1
2013 2
2014 1
2015 1
2016 3
2017 3
2018 2
2019 3
2020 1
2021 1
2023 2
2025 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

17 results

Results by year

Citations

1 article found by citation matching

Search results

Filters applied: . Clear all
Page 1
Depletion of myeloid cells exacerbates hepatitis and induces an aberrant increase in histone H3 in mouse serum.
Piao X, Yamazaki S, Komazawa-Sakon S, Miyake S, Nakabayashi O, Kurosawa T, Mikami T, Tanaka M, Van Rooijen N, Ohmuraya M, Oikawa A, Kojima Y, Kakuta S, Uchiyama Y, Tanaka M, Nakano H. Piao X, et al. Hepatology. 2017 Jan;65(1):237-252. doi: 10.1002/hep.28878. Epub 2016 Nov 25. Hepatology. 2017. PMID: 27770461
Depletion of Kupffer cells (KCs) by clodronate liposomes did not impair clearance of dying hepatocytes or exacerbate hepatitis in Cflar(Hep-low) mice. ...CONCLUSION: These findings indicate an unexpected role of myeloid cells in decreasin …
Depletion of Kupffer cells (KCs) by clodronate liposomes did not impair clearance of dying hepatocytes or exacerbate …
Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use.
Bukong TN, Cho Y, Iracheta-Vellve A, Saha B, Lowe P, Adejumo A, Furi I, Ambade A, Gyongyosi B, Catalano D, Kodys K, Szabo G. Bukong TN, et al. J Hepatol. 2018 Nov;69(5):1145-1154. doi: 10.1016/j.jhep.2018.07.005. Epub 2018 Jul 18. J Hepatol. 2018. PMID: 30030149 Free PMC article.
In vivo, anti-Ly6G antibody (IA8) was used for neutrophil depletion. RESULTS: Inducers of NETs (endotoxin and bacterial DNA) significantly increased in the circulation after binge alcohol drinking in humans. ...In vitro alcohol treatment reduced efferocytosis and ph …
In vivo, anti-Ly6G antibody (IA8) was used for neutrophil depletion. RESULTS: Inducers of NETs (endotoxin and bacterial DNA) s …
Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis.
Farooq M, Filliol A, Simoes Eugénio M, Piquet-Pellorce C, Dion S, Raguenes-Nicol C, Jan A, Dimanche-Boitrel MT, Le Seyec J, Samson M. Farooq M, et al. Cell Death Dis. 2019 Jan 8;10(1):12. doi: 10.1038/s41419-018-1277-3. Cell Death Dis. 2019. PMID: 30622241 Free PMC article.
The protein kinase RIPK1 plays a crucial role at the crossroad of stress-induced signaling pathways that affects cell's decision to live or die. The present study aimed to define the role of RIPK1 in hepatocytes during fulminant viral hepatitis, a worldwide s …
The protein kinase RIPK1 plays a crucial role at the crossroad of stress-induced signaling pathways that affects cell's decision to l …
Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis.
Carrière V, Arshad MI, Le Seyec J, Lefevre B, Farooq M, Jan A, Manuel C, Touami-Bernard L, Lucas-Clerc C, Genet V, Gascan H, Girard JP, Chalmel F, Lamontagne L, Piquet-Pellorce C, Samson M. Carrière V, et al. Mediators Inflamm. 2017;2017:1359064. doi: 10.1155/2017/1359064. Epub 2017 May 4. Mediators Inflamm. 2017. PMID: 28607531 Free PMC article.
The IL-33 KO mice were more sensitive to L2-MHV3 infection exhibiting higher levels of AST/ALT, higher tissue damage, significant weight loss, and earlier death. An increased depletion of B and T lymphocytes, NKT cells, dendritic cells, and macrophages was ob …
The IL-33 KO mice were more sensitive to L2-MHV3 infection exhibiting higher levels of AST/ALT, higher tissue damage, significant weight los …
Activation and increase of radio-sensitive CD11b+ recruited Kupffer cells/macrophages in diet-induced steatohepatitis in FGF5 deficient mice.
Nakashima H, Nakashima M, Kinoshita M, Ikarashi M, Miyazaki H, Hanaka H, Imaki J, Seki S. Nakashima H, et al. Sci Rep. 2016 Oct 6;6:34466. doi: 10.1038/srep34466. Sci Rep. 2016. PMID: 27708340 Free PMC article.
We have recently reported that Kupffer cells consist of two subsets, radio-resistant resident CD68+ Kupffer cells and radio-sensitive recruited CD11b+ Kupffer cells/macrophages (Mphis). ...Intermittent exposure to 1 Gy irradiation markedly decreased these Mph …
We have recently reported that Kupffer cells consist of two subsets, radio-resistant resident CD68+ Kupffer cells and radio-se …
CRIg(+) Macrophages Prevent Gut Microbial DNA-Containing Extracellular Vesicle-Induced Tissue Inflammation and Insulin Resistance.
Luo Z, Ji Y, Gao H, Gomes Dos Reis FC, Bandyopadhyay G, Jin Z, Ly C, Chang YJ, Zhang D, Kumar D, Ying W. Luo Z, et al. Gastroenterology. 2021 Feb;160(3):863-874. doi: 10.1053/j.gastro.2020.10.042. Epub 2020 Nov 2. Gastroenterology. 2021. PMID: 33152356 Free PMC article.
Liver CRIg(+) macrophages efficiently clear mEVs from the bloodstream through a C3-dependent opsonization mechanism, whereas obesity elicits a marked reduction in the CRIg(+) macrophage population. Depletion of CRIg(+) cells results in the spread of mEVs into distan …
Liver CRIg(+) macrophages efficiently clear mEVs from the bloodstream through a C3-dependent opsonization mechanism, whereas obesity elicits …
Opposing effects of prednisolone treatment on T/NKT cell- and hepatotoxin-mediated hepatitis in mice.
Kwon HJ, Won YS, Park O, Feng D, Gao B. Kwon HJ, et al. Hepatology. 2014 Mar;59(3):1094-106. doi: 10.1002/hep.26748. Epub 2014 Jan 21. Hepatology. 2014. PMID: 24115096 Free PMC article.
Prednisolone administration attenuated ConA- and alpha-GalCer-induced hepatitis and systemic inflammatory responses. Treating mice with prednisolone also suppressed inflammatory responses in a model of hepatotoxin (CCl4 )-induced hepatitis, but surpris …
Prednisolone administration attenuated ConA- and alpha-GalCer-induced hepatitis and systemic inflammatory responses. Treating …
Fibrinogen-like protein 2 regulates macrophage glycolytic reprogramming by directly targeting PKM2 and exacerbates alcoholic liver injury.
Hu X, Wan X, Diao Y, Shen Z, Zhang Z, Wang P, Hu D, Wang X, Yan W, Yu C, Luo X, Wang H, Ning Q. Hu X, et al. Int Immunopharmacol. 2023 Nov;124(Pt B):110957. doi: 10.1016/j.intimp.2023.110957. Epub 2023 Sep 19. Int Immunopharmacol. 2023. PMID: 37734200
RESULTS: Expression of Fgl2 was elevated in macrophages of livers from mice with chronic-binge ethanol feeding or patients with alcoholic hepatitis. Fgl2 depletion ameliorated ethanol diet-induced hepatic steatosis and oxidative injury as well as the levels o …
RESULTS: Expression of Fgl2 was elevated in macrophages of livers from mice with chronic-binge ethanol feeding or patients with alcoholic …
Invariant NKT cell activation induces neutrophil accumulation and hepatitis: opposite regulation by IL-4 and IFN-gamma.
Wang H, Feng D, Park O, Yin S, Gao B. Wang H, et al. Hepatology. 2013 Oct;58(4):1474-85. doi: 10.1002/hep.26471. Epub 2013 Aug 6. Hepatology. 2013. PMID: 23686838 Free PMC article.
In contrast, genetic deletion of IFN-gamma, the IFN-gamma receptor, or its downstream signaling molecule STAT1 enhanced liver neutrophil accumulation, thereby exacerbating liver injury and hepatitis. Moreover, depletion of neutrophils eradicated alpha-Galcer- …
In contrast, genetic deletion of IFN-gamma, the IFN-gamma receptor, or its downstream signaling molecule STAT1 enhanced liver neutrophil acc …
RIPK1 protects hepatocytes from Kupffer cells-mediated TNF-induced apoptosis in mouse models of PAMP-induced hepatitis.
Filliol A, Piquet-Pellorce C, Raguénès-Nicol C, Dion S, Farooq M, Lucas-Clerc C, Vandenabeele P, Bertrand MJM, Le Seyec J, Samson M. Filliol A, et al. J Hepatol. 2017 Jun;66(6):1205-1213. doi: 10.1016/j.jhep.2017.01.005. Epub 2017 Jan 11. J Hepatol. 2017. PMID: 28088582 Free article.
BACKGROUND & AIMS: The severity of liver diseases is exacerbated by the death of hepatocytes, which can be induced by the sensing of pathogen associated molecular patterns (PAMPs) derived from the gut microbiota. ...In this study, we investigated the role of the …
BACKGROUND & AIMS: The severity of liver diseases is exacerbated by the death of hepatocytes, which can be induced by the …
17 results