Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis.
Carrière V, Arshad MI, Le Seyec J, Lefevre B, Farooq M, Jan A, Manuel C, Touami-Bernard L, Lucas-Clerc C, Genet V, Gascan H, Girard JP, Chalmel F, Lamontagne L, Piquet-Pellorce C, Samson M.
Carrière V, et al.
Mediators Inflamm. 2017;2017:1359064. doi: 10.1155/2017/1359064. Epub 2017 May 4.
Mediators Inflamm. 2017.
PMID: 28607531
Free PMC article.
The IL-33 KO mice were more sensitive to L2-MHV3 infection exhibiting higher levels of AST/ALT, higher tissue damage, significant weight loss, and earlier death. An increased depletion of B and T lymphocytes, NKT cells, dendritic cells, and macrophages was ob …
The IL-33 KO mice were more sensitive to L2-MHV3 infection exhibiting higher levels of AST/ALT, higher tissue damage, significant weight los …