Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 3
2004 2
2005 1
2006 1
2007 2
2008 4
2009 3
2010 1
2011 1
2012 1
2013 1
2014 3
2015 2
2016 2
2017 2
2018 1
2019 3
2020 2
2021 2
2022 4
2023 1
2024 5
2025 2
2026 3

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

47 results

Results by year

Filters applied: . Clear all
Page 1
ERAP Inhibitors in Autoimmunity and Immuno-Oncology: Medicinal Chemistry Insights.
Fougiaxis V, He B, Khan T, Vatinel R, Koutroumpa NM, Afantitis A, Lesire L, Sierocki P, Deprez B, Deprez-Poulain R. Fougiaxis V, et al. Among authors: deprez poulain r. J Med Chem. 2024 Jul 25;67(14):11597-11621. doi: 10.1021/acs.jmedchem.4c00840. Epub 2024 Jul 16. J Med Chem. 2024. PMID: 39011823 Free PMC article. Review.
First fragment-based screening identifies new chemotypes inhibiting ERAP1-metalloprotease.
Fougiaxis V, Barcherini V, Petrovic MM, Sierocki P, Warenghem S, Leroux F, Bou Karroum N, Petit-Cancelier F, Rodeschini V, Roche D, Deprez B, Deprez-Poulain R. Fougiaxis V, et al. Among authors: deprez poulain r. Eur J Med Chem. 2024 Dec 15;280:116926. doi: 10.1016/j.ejmech.2024.116926. Epub 2024 Sep 30. Eur J Med Chem. 2024. PMID: 39369482 Free article.
Facts, figures and trends in lead generation.
Deprez-Poulain R, Deprez B. Deprez-Poulain R, et al. Curr Top Med Chem. 2004;4(6):569-80. doi: 10.2174/1568026043451168. Curr Top Med Chem. 2004. PMID: 14965294 Review.
Identification of indole-based activators of insulin degrading enzyme.
Kraupner N, Dinh CP, Wen X, Landry V, Herledan A, Leroux F, Bosc D, Charton J, Maillard C, Warenghem S, Duplan I, Piveteau C, Hennuyer N, Staels B, Deprez B, Deprez-Poulain R. Kraupner N, et al. Among authors: deprez poulain r. Eur J Med Chem. 2022 Jan 15;228:113982. doi: 10.1016/j.ejmech.2021.113982. Epub 2021 Nov 16. Eur J Med Chem. 2022. PMID: 34815130
Discovery of New Nanomolar Selective IRAP Inhibitors.
He B, Karroum NB, Gealageas R, Mauvais FX, Warenghem S, Roignant M, Kraupner N, Lam BV, Azaroual N, Ultré V, Rech A, Lesire L, Couturier C, Leroux F, van Endert P, Deprez B, Deprez-Poulain R. He B, et al. Among authors: deprez poulain r. J Med Chem. 2025 Feb 27;68(4):4168-4195. doi: 10.1021/acs.jmedchem.4c01744. Epub 2025 Feb 7. J Med Chem. 2025. PMID: 39916550 Free PMC article.
Kinetic Target-Guided Synthesis: Reaching the Age of Maturity.
Bosc D, Camberlein V, Gealageas R, Castillo-Aguilera O, Deprez B, Deprez-Poulain R. Bosc D, et al. Among authors: deprez poulain r. J Med Chem. 2020 Apr 23;63(8):3817-3833. doi: 10.1021/acs.jmedchem.9b01183. Epub 2019 Dec 24. J Med Chem. 2020. PMID: 31820982 Review.
Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin-degrading enzyme, a new molecular vulnerability in multiple myeloma.
Lesire L, Deprez-Poulain R, Bosc D, Leroux F, Landry V, Ourabah S, Tardy M, Maillard C, Gealageas R, Dumont J, Herledan A, Warenghem S, Cruette M, Lenglart C, Biela A, Piveteau C, De Smedt E, Muylaert C, Liang W, De Paco EG, Alaterre E, Ovejero S, Robert N, Delahaye F, Tang WJ, van Endert P, De Bruyne E, Moreaux J, Deprez B. Lesire L, et al. Among authors: deprez poulain r. Br J Pharmacol. 2026 Jun;183(12):3355-3376. doi: 10.1111/bph.70407. Epub 2026 Mar 19. Br J Pharmacol. 2026. PMID: 41852107
Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis.
Camberlein V, Fléau C, Sierocki P, Li L, Gealageas R, Bosc D, Guillaume V, Warenghem S, Leroux F, Rosell M, Cheng K, Medve L, Prigent M, Decanter M, Piveteau C, Biela A, Eveque M, Dumont J, Mpakali A, Giastas P, Herledan A, Couturier C, Haupenthal J, Lesire L, Hirsch AKH, Deprez B, Stratikos E, Bouvier M, Deprez-Poulain R. Camberlein V, et al. Among authors: deprez poulain r. Angew Chem Int Ed Engl. 2022 Sep 26;61(39):e202203560. doi: 10.1002/anie.202203560. Epub 2022 Aug 19. Angew Chem Int Ed Engl. 2022. PMID: 35904863 Free PMC article.
47 results