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Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells.
Kozela E, Juknat A, Gao F, Kaushansky N, Coppola G, Vogel Z. Kozela E, et al. J Neuroinflammation. 2016 Jun 3;13(1):136. doi: 10.1186/s12974-016-0603-x. J Neuroinflammation. 2016. PMID: 27256343 Free PMC article.
BACKGROUND: Our previous studies showed that the non-psychoactive cannabinoid, cannabidiol (CBD), ameliorates the clinical symptoms in mouse myelin oligodendrocyte glycoprotein (MOG)35-55-induced experimental autoimmune encephalomyelitis model of multi …
BACKGROUND: Our previous studies showed that the non-psychoactive cannabinoid, cannabidiol (CBD), ameliorates th …
HU-446 and HU-465, Derivatives of the Non-psychoactive Cannabinoid Cannabidiol, Decrease the Activation of Encephalitogenic T Cells.
Kozela E, Haj C, Hanuš L, Chourasia M, Shurki A, Juknat A, Kaushansky N, Mechoulam R, Vogel Z. Kozela E, et al. Chem Biol Drug Des. 2016 Jan;87(1):143-53. doi: 10.1111/cbdd.12637. Epub 2015 Sep 16. Chem Biol Drug Des. 2016. PMID: 26259697
Cannabidiol (CBD), the non-psychoactive cannabinoid, has been previously shown by us to decrease peripheral inflammation and neuroinflammation in mouse experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS). Here we hav …
Cannabidiol (CBD), the non-psychoactive cannabinoid, has been previously shown by us to decrease peripher …
Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - studies in BV-2 microglia and encephalitogenic T cells.
Juknat A, Kozela E, Kaushansky N, Mechoulam R, Vogel Z. Juknat A, et al. J Basic Clin Physiol Pharmacol. 2016 May 1;27(3):289-96. doi: 10.1515/jbcpp-2015-0071. J Basic Clin Physiol Pharmacol. 2016. PMID: 26540221 Free article.
BACKGROUND: Dimethylheptyl-cannabidiol (DMH-CBD), a non-psychoactive, synthetic derivative of the phytocannabinoid cannabidiol (CBD), has been reported to be anti-inflammatory in RAW macrophages. ...In addition, DMH-CBD decreases the prol …
BACKGROUND: Dimethylheptyl-cannabidiol (DMH-CBD), a non-psychoactive, synthetic derivative of the phytocannabino …