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p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice.
Tenhagen M, Klarenbeek S, Braumuller TM, Hofmann I, van der Groep P, Ter Hoeve N, van der Wall E, Jonkers J, Derksen PW. Tenhagen M, et al. Among authors: derksen pw. J Mammary Gland Biol Neoplasia. 2016 Dec;21(3-4):81-88. doi: 10.1007/s10911-016-9358-3. Epub 2016 Jul 13. J Mammary Gland Biol Neoplasia. 2016. PMID: 27411687 Free PMC article.
Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.
Derksen PW, Liu X, Saridin F, van der Gulden H, Zevenhoven J, Evers B, van Beijnum JR, Griffioen AW, Vink J, Krimpenfort P, Peterse JL, Cardiff RD, Berns A, Jonkers J. Derksen PW, et al. Cancer Cell. 2006 Nov;10(5):437-49. doi: 10.1016/j.ccr.2006.09.013. Cancer Cell. 2006. PMID: 17097565 Free article.
Modeling metastatic breast cancer in mice.
Jonkers J, Derksen PW. Jonkers J, et al. Among authors: derksen pw. J Mammary Gland Biol Neoplasia. 2007 Sep;12(2-3):191-203. doi: 10.1007/s10911-007-9050-8. J Mammary Gland Biol Neoplasia. 2007. PMID: 17587153 Free article. Review.
Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.
Evers B, Drost R, Schut E, de Bruin M, van der Burg E, Derksen PW, Holstege H, Liu X, van Drunen E, Beverloo HB, Smith GC, Martin NM, Lau A, O'Connor MJ, Jonkers J. Evers B, et al. Among authors: derksen pw. Clin Cancer Res. 2008 Jun 15;14(12):3916-25. doi: 10.1158/1078-0432.CCR-07-4953. Clin Cancer Res. 2008. PMID: 18559613 Free article.
NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin.
Lehembre F, Yilmaz M, Wicki A, Schomber T, Strittmatter K, Ziegler D, Kren A, Went P, Derksen PW, Berns A, Jonkers J, Christofori G. Lehembre F, et al. Among authors: derksen pw. EMBO J. 2008 Oct 8;27(19):2603-15. doi: 10.1038/emboj.2008.178. Epub 2008 Sep 4. EMBO J. 2008. PMID: 18772882 Free PMC article.
High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs.
Rottenberg S, Jaspers JE, Kersbergen A, van der Burg E, Nygren AO, Zander SA, Derksen PW, de Bruin M, Zevenhoven J, Lau A, Boulter R, Cranston A, O'Connor MJ, Martin NM, Borst P, Jonkers J. Rottenberg S, et al. Among authors: derksen pw. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17079-84. doi: 10.1073/pnas.0806092105. Epub 2008 Oct 29. Proc Natl Acad Sci U S A. 2008. PMID: 18971340 Free PMC article.
77 results