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Designing development programs for non-traditional antibacterial agents.
Rex JH, Fernandez Lynch H, Cohen IG, Darrow JJ, Outterson K. Rex JH, et al. Nat Commun. 2019 Jul 31;10(1):3416. doi: 10.1038/s41467-019-11303-9. Nat Commun. 2019. PMID: 31366924 Free PMC article. Review.
In the face of rising rates of antibacterial resistance, many responses are being pursued in parallel, including 'non-traditional' antibacterial agents (agents that are not small-molecule drugs and/or do not act by directly targeting bact …
In the face of rising rates of antibacterial resistance, many responses are being pursued in parallel, including 'non-tradi …
Antibiotics in the clinical pipeline as of December 2022.
Butler MS, Henderson IR, Capon RJ, Blaskovich MAT. Butler MS, et al. J Antibiot (Tokyo). 2023 Aug;76(8):431-473. doi: 10.1038/s41429-023-00629-8. Epub 2023 Jun 8. J Antibiot (Tokyo). 2023. PMID: 37291465 Free PMC article. Review.
The need for new antibacterial drugs to treat the increasing global prevalence of drug-resistant bacterial infections has clearly attracted global attention, with a range of existing and upcoming funding, policy, and legislative initiatives designed to revive ant …
The need for new antibacterial drugs to treat the increasing global prevalence of drug-resistant bacterial infections has clearly att …
Bacteriophage therapy in musculoskeletal infections: from basic science to clinical application.
Ferry T, Onsea J, Roussel-Gaillard T, Batailler C, Moriarty TF, Metsemakers WJ. Ferry T, et al. EFORT Open Rev. 2024 May 10;9(5):339-348. doi: 10.1530/EOR-24-0042. EFORT Open Rev. 2024. PMID: 38726986 Free PMC article. Review.
The emergence of antimicrobial resistance (AMR) adds to the complexity of the problem, leading to increased morbidity and healthcare expenses. There is an urgent need for novel antibacterial strategies, with the World Health Organization endorsing non-traditional …
The emergence of antimicrobial resistance (AMR) adds to the complexity of the problem, leading to increased morbidity and healthcare expense …
Strategies for older people living in care homes to prevent urinary tract infection: the StOP UTI realist synthesis.
Prieto J, Wilson J, Tingle A, Cooper E, Handley M, Rycroft-Malone J, Bostock J, Williams L, Loveday H. Prieto J, et al. Health Technol Assess. 2024 Oct;28(68):1-139. doi: 10.3310/DADT3410. Health Technol Assess. 2024. PMID: 39432412 Free PMC article. Review.
It accounts for more than 50% of antibiotic prescriptions in care homes and is a frequent reason for care home residents being hospitalised. OBJECTIVE: This realist review developed and refined programme theories for preventing and recognising urinary tract infectio …
It accounts for more than 50% of antibiotic prescriptions in care homes and is a frequent reason for care home residents being hospitalised. …