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Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: application to the assessment of CYP2D6 activity in fibromyalgia patients.
Daali Y, Cherkaoui S, Doffey-Lazeyras F, Dayer P, Desmeules JA. Daali Y, et al. Among authors: desmeules ja. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Jan 1;861(1):56-63. doi: 10.1016/j.jchromb.2007.11.019. Epub 2007 Nov 23. J Chromatogr B Analyt Technol Biomed Life Sci. 2008. PMID: 18065299
Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety.
Samer CF, Daali Y, Wagner M, Hopfgartner G, Eap CB, Rebsamen MC, Rossier MF, Hochstrasser D, Dayer P, Desmeules JA. Samer CF, et al. Among authors: desmeules ja. Br J Pharmacol. 2010 Jun;160(4):919-30. doi: 10.1111/j.1476-5381.2010.00709.x. Br J Pharmacol. 2010. PMID: 20590588 Free PMC article. Clinical Trial.
211 results