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Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer.
Asmann YW, Necela BM, Kalari KR, Hossain A, Baker TR, Carr JM, Davis C, Getz JE, Hostetter G, Li X, McLaughlin SA, Radisky DC, Schroth GP, Cunliffe HE, Perez EA, Thompson EA. Asmann YW, et al. Cancer Res. 2012 Apr 15;72(8):1921-8. doi: 10.1158/0008-5472.CAN-11-3142. Epub 2012 Apr 10. Cancer Res. 2012. PMID: 22496456
Among the redundant fusion transcripts, 7 were unique to ER(+) tumors and 8 were unique to triple-negative tumors. In contrast, none of the redundant fusion transcripts were unique to HER2(+) tumors. Both private and redundant f
Among the redundant fusion transcripts, 7 were unique to ER(+) tumors and 8 were unique to triple-negative tumors. In c …
The ARABIDOPSIS SKP1-LIKE1 (ASK1) protein acts predominately from leptotene to pachytene and represses homologous recombination in male meiosis.
Wang Y, Yang M. Wang Y, et al. Planta. 2006 Feb;223(3):613-7. doi: 10.1007/s00425-005-0154-3. Epub 2005 Nov 9. Planta. 2006. PMID: 16283376
Normal progression of genetic recombination requires timely degradation of many proteins, but little is known about the proteolytic mechanism. ...We provide evidence in this report that ASK1 is predominately expressed from leptotene to pachytene, and negatively regulates r …
Normal progression of genetic recombination requires timely degradation of many proteins, but little is known about the proteolytic m …