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Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond.
Holderfield M, Deuker MM, McCormick F, McMahon M. Holderfield M, et al. Among authors: deuker mm. Nat Rev Cancer. 2014 Jul;14(7):455-67. doi: 10.1038/nrc3760. Nat Rev Cancer. 2014. PMID: 24957944 Free PMC article. Review.
Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma.
Marsh Durban V, Deuker MM, Bosenberg MW, Phillips W, McMahon M. Marsh Durban V, et al. Among authors: deuker mm. J Clin Invest. 2013 Dec;123(12):5104-18. doi: 10.1172/JCI69619. Epub 2013 Nov 8. J Clin Invest. 2013. PMID: 24200692 Free PMC article.
PIK3CA-mutated melanoma cells rely on cooperative signaling through mTORC1/2 for sustained proliferation.
Silva JM, Deuker MM, Baguley BC, McMahon M. Silva JM, et al. Among authors: deuker mm. Pigment Cell Melanoma Res. 2017 May;30(3):353-367. doi: 10.1111/pcmr.12586. Epub 2017 Apr 20. Pigment Cell Melanoma Res. 2017. PMID: 28233937 Free PMC article.
Rational targeting of BRAF and PI3-Kinase signaling for melanoma therapy.
Deuker MM, McMahon M. Deuker MM, et al. Mol Cell Oncol. 2015 May 7;3(3):e1033095. doi: 10.1080/23723556.2015.1033095. eCollection 2016 May. Mol Cell Oncol. 2015. PMID: 27314067 Free PMC article.
Cancer biology: Enzyme meets a surprise target.
Deuker MM, McMahon M. Deuker MM, et al. Nature. 2014 Jun 12;510(7504):225-6. doi: 10.1038/nature13343. Epub 2014 May 21. Nature. 2014. PMID: 24847879 Free PMC article. No abstract available.
Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein.
Deuker MM, Lewis KN, Ingaramo M, Kimmel J, Buffenstein R, Settleman J. Deuker MM, et al. Sci Rep. 2020 Apr 24;10(1):6966. doi: 10.1038/s41598-020-64009-0. Sci Rep. 2020. PMID: 32332849 Free PMC article.
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