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Development of a 3D matrix for modeling mammalian spinal cord injury in vitro.
Diaz Quiroz JF, Li Y, Aparicio C, Echeverri K. Diaz Quiroz JF, et al. Neural Regen Res. 2016 Nov;11(11):1810-1815. doi: 10.4103/1673-5374.194751. Neural Regen Res. 2016. PMID: 28123426 Free PMC article.
Spinal cord injury is usually modeled in rats and mice using contusion or complete transection models and this has led to a deeper understanding of the molecular and cellular complexities of the injury. ...Here we developed a colla
Spinal cord injury is usually modeled in rats and mice using contusion or complete transection models and
Engineering biomaterial microenvironments to promote myelination in the central nervous system.
Unal DB, Caliari SR, Lampe KJ. Unal DB, et al. Brain Res Bull. 2019 Oct;152:159-174. doi: 10.1016/j.brainresbull.2019.07.013. Epub 2019 Jul 12. Brain Res Bull. 2019. PMID: 31306690 Review.
Promoting remyelination and/or minimizing demyelination are key therapeutic strategies under investigation for diseases and injuries like multiple sclerosis (MS), spinal cord injury, stroke, and virus-induced encephalopathy. ...In particular, stiffness …
Promoting remyelination and/or minimizing demyelination are key therapeutic strategies under investigation for diseases and injuries
Spinal cord injury elicits expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors.
Jones LL, Tuszynski MH. Jones LL, et al. J Neurosci. 2002 Jun 1;22(11):4611-24. doi: 10.1523/JNEUROSCI.22-11-04611.2002. J Neurosci. 2002. PMID: 12040068 Free PMC article.
Keratan sulfate proteoglycans (KSPGs) are extracellular matrix molecules that appear to establish boundaries for axonal growth in the developing brain and spinal cord. ...The aim of the current study was to investigate whether KSPGs are expresse …
Keratan sulfate proteoglycans (KSPGs) are extracellular matrix molecules that appear to establish boundaries for axonal growth
Evaluation of biomaterials for bladder augmentation using cystometric analyses in various rodent models.
Tu DD, Seth A, Gil ES, Kaplan DL, Mauney JR, Estrada CR Jr. Tu DD, et al. J Vis Exp. 2012 Aug 9;(66):3981. doi: 10.3791/3981. J Vis Exp. 2012. PMID: 22907252 Free PMC article.
A number of congenital and acquired urological anomalies including posterior urethral valves, benign prostatic hyperplasia, and neurogenic bladder secondary to spina bifida/spinal cord injury can result in pathologic tissue remodeling leading to impaired comp …
A number of congenital and acquired urological anomalies including posterior urethral valves, benign prostatic hyperplasia, and neurogenic b …
Influence of cross-linked hyaluronic acid hydrogels on neurite outgrowth and recovery from spinal cord injury.
Horn EM, Beaumont M, Shu XZ, Harvey A, Prestwich GD, Horn KM, Gibson AR, Preul MC, Panitch A. Horn EM, et al. J Neurosurg Spine. 2007 Feb;6(2):133-40. doi: 10.3171/spi.2007.6.2.133. J Neurosurg Spine. 2007. PMID: 17330580
Hyaluronic acid (HA), a nonsulfated glycosaminoglycan ubiquitous in all tissues, was investigated as a potential neural tissue engineering matrix. METHODS: Chick dorsal root ganglia were cultured in 3D hydrogel matrices composed of cross-linked thiol-modified HA or …
Hyaluronic acid (HA), a nonsulfated glycosaminoglycan ubiquitous in all tissues, was investigated as a potential neural tissue engineering …