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X-linked IAP is a direct inhibitor of cell-death proteases.
Deveraux QL, Takahashi R, Salvesen GS, Reed JC. Deveraux QL, et al. Nature. 1997 Jul 17;388(6639):300-4. doi: 10.1038/40901. Nature. 1997. PMID: 9230442
Pro-caspase-3 is a major physiologic target of caspase-8.
Stennicke HR, Jürgensmeier JM, Shin H, Deveraux Q, Wolf BB, Yang X, Zhou Q, Ellerby HM, Ellerby LM, Bredesen D, Green DR, Reed JC, Froelich CJ, Salvesen GS. Stennicke HR, et al. J Biol Chem. 1998 Oct 16;273(42):27084-90. doi: 10.1074/jbc.273.42.27084. J Biol Chem. 1998. PMID: 9765224
A single BIR domain of XIAP sufficient for inhibiting caspases.
Takahashi R, Deveraux Q, Tamm I, Welsh K, Assa-Munt N, Salvesen GS, Reed JC. Takahashi R, et al. J Biol Chem. 1998 Apr 3;273(14):7787-90. doi: 10.1074/jbc.273.14.7787. J Biol Chem. 1998. PMID: 9525868
Bax directly induces release of cytochrome c from isolated mitochondria.
Jürgensmeier JM, Xie Z, Deveraux Q, Ellerby L, Bredesen D, Reed JC. Jürgensmeier JM, et al. Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):4997-5002. doi: 10.1073/pnas.95.9.4997. Proc Natl Acad Sci U S A. 1998. PMID: 9560217 Free PMC article.
Purification and use of recombinant inhibitor of apoptosis proteins as caspase inhibitors.
Deveraux QL, Welsh K, Reed JC. Deveraux QL, et al. Methods Enzymol. 2000;322:154-61. doi: 10.1016/s0076-6879(00)22015-6. Methods Enzymol. 2000. PMID: 10914012 No abstract available.
Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis.
Matsuyama S, Llopis J, Deveraux QL, Tsien RY, Reed JC. Matsuyama S, et al. Among authors: deveraux ql. Nat Cell Biol. 2000 Jun;2(6):318-25. doi: 10.1038/35014006. Nat Cell Biol. 2000. PMID: 10854321
Evolutionary conservation of apoptosis mechanisms: lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9.
Huang Q, Deveraux QL, Maeda S, Salvesen GS, Stennicke HR, Hammock BD, Reed JC. Huang Q, et al. Among authors: deveraux ql. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1427-32. doi: 10.1073/pnas.97.4.1427. Proc Natl Acad Sci U S A. 2000. PMID: 10677478 Free PMC article.
Endogenous inhibitors of caspases.
Deveraux QL, Stennicke HR, Salvesen GS, Reed JC. Deveraux QL, et al. J Clin Immunol. 1999 Nov;19(6):388-98. doi: 10.1023/a:1020502800208. J Clin Immunol. 1999. PMID: 10634212 Review.
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases.
Deveraux QL, Leo E, Stennicke HR, Welsh K, Salvesen GS, Reed JC. Deveraux QL, et al. EMBO J. 1999 Oct 1;18(19):5242-51. doi: 10.1093/emboj/18.19.5242. EMBO J. 1999. PMID: 10508158 Free PMC article.
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia.
Krajewski S, Krajewska M, Ellerby LM, Welsh K, Xie Z, Deveraux QL, Salvesen GS, Bredesen DE, Rosenthal RE, Fiskum G, Reed JC. Krajewski S, et al. Among authors: deveraux ql. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5752-7. doi: 10.1073/pnas.96.10.5752. Proc Natl Acad Sci U S A. 1999. PMID: 10318956 Free PMC article.
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