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Molecular mechanism of complement inhibition by the trypanosome receptor ISG65.
Cook AD, Carrington M, Higgins MK. Cook AD, et al. Elife. 2024 Apr 24;12:RP88960. doi: 10.7554/eLife.88960. Elife. 2024. PMID: 38655765
African trypanosomes replicate within infected mammals where they are exposed to the complement system. This system centres around complement C3, which is present in a soluble form in serum but becomes covalently deposited onto the surfaces of pathogens after proteolytic c …
African trypanosomes replicate within infected mammals where they are exposed to the complement system. This system centres around complemen …
Regioselective C(sp2)-H halogenation of pyrazolo[1,5-a]pyrimidines facilitated by hypervalent iodine(iii) under aqueous and ambient conditions.
Chillal AS, Bhawale RT, Kshirsagar UA. Chillal AS, et al. RSC Adv. 2024 Apr 23;14(19):13095-13099. doi: 10.1039/d4ra02090a. eCollection 2024 Apr 22. RSC Adv. 2024. PMID: 38655480 Free PMC article.
An efficient and mild approach has been developed for the regio-selective direct C3 halogenation of pyrazolo[1,5-a]pyrimidines employing readily available potassium halide salts and a hypervalent iodine(iii) reagent at ambient temperature. The protocol is both practical an …
An efficient and mild approach has been developed for the regio-selective direct C3 halogenation of pyrazolo[1,5-a]pyrimidines employ …
Bioorthogonal Cu Single-atom Nanozyme for Synergistic Nanocatalytic Therapy, Photothermal Therapy, Cuproptosis, and Immunotherapy.
Wu L, Lin H, Cao X, Tong Q, Yang F, Miao Y, Ye D, Fan Q. Wu L, et al. Angew Chem Int Ed Engl. 2024 Apr 23:e202405937. doi: 10.1002/anie.202405937. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38654446
Using this method, sputtered copper (Cu) SAzymes (CuSA) is developed with unreported unique planar Cu-C3 coordinated configuration. To enhance the tumor-specific targeting, we employ a bioorthogonal approach to engineer CuSA, denoted as CuSACO. ...
Using this method, sputtered copper (Cu) SAzymes (CuSA) is developed with unreported unique planar Cu-C3 coordinated configuration. T …
Evaluation of power wheelchair driving performance in simulator compared to driving in real-life situations: the SIMADAPT (simulator ADAPT) project-a pilot study.
Fraudet B, Leblong E, Piette P, Nicolas B, Gouranton V, Babel M, Devigne L, Pasteau F, Gallien P. Fraudet B, et al. J Neuroeng Rehabil. 2024 Apr 23;21(1):60. doi: 10.1186/s12984-024-01354-5. J Neuroeng Rehabil. 2024. PMID: 38654367
METHODS: Three driving circuits of progressive difficulty levels (C1, C2, C3) that were elaborated to assess the driving performances with PWC in indoor situations, were used in this study. ...The driving performances between VR and R conditions were statistically differen …
METHODS: Three driving circuits of progressive difficulty levels (C1, C2, C3) that were elaborated to assess the driving performances …
Plant endophytic fungi exhibit diverse biotransformation pathways of mogrosides and show great potential application in siamenoside I production.
Lin W, Jiang Q, Dong Y, Xiao Y, Wang Y, Gao B, Zhu D. Lin W, et al. Bioresour Bioprocess. 2024 Apr 23;11(1):42. doi: 10.1186/s40643-024-00754-8. Bioresour Bioprocess. 2024. PMID: 38653936
Mogroside V, the primary active compound in Siraitia grosvenorii fruit, can be converted into other various bioactive mogrosides by selective hydrolysis of glucose residues at C3 and C24 positions. In present study, 20 fungal strains were randomly selected from our endophy …
Mogroside V, the primary active compound in Siraitia grosvenorii fruit, can be converted into other various bioactive mogrosides by selectiv …
Pembrolizumab Plus Binimetinib With or Without Chemotherapy for MSS/pMMR Metastatic Colorectal Cancer: Outcomes From KEYNOTE-651 Cohorts A, C, and E.
Chen EX, Kavan P, Tehfe M, Kortmansky JS, Sawyer MB, Chiorean EG, Lieu CH, Polite B, Wong L, Fakih M, Spencer K, Chaves J, Li C, Leconte P, Adelberg D, Kim R. Chen EX, et al. Clin Colorectal Cancer. 2024 Apr 1:S1533-0028(24)00024-0. doi: 10.1016/j.clcc.2024.03.002. Online ahead of print. Clin Colorectal Cancer. 2024. PMID: 38653648
Groundwater hydrochemistry, source identification and health assessment based on self-organizing map in an intensive mining area in Shanxi, China.
Shang Y, Fu C, Zhang W, Li X, Li X. Shang Y, et al. Environ Res. 2024 Apr 21:118934. doi: 10.1016/j.envres.2024.118934. Online ahead of print. Environ Res. 2024. PMID: 38653438
The results showed that the groundwater chemical characteristics were categorized into 48 neurons grouped into six clusters (C1-C6) representing different groundwater types with different contamination characteristics. C1, C3, and C5 represent uncontaminated or minimally c …
The results showed that the groundwater chemical characteristics were categorized into 48 neurons grouped into six clusters (C1-C6) represen …
89,227 results
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