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The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex.
Carr RM, Romecin Duran PA, Tolosa EJ, Ma C, Oseini AM, Moser CD, Banini BA, Huang J, Asumda F, Dhanasekaran R, Graham RP, Toruner MD, Safgren SL, Almada LL, Wang S, Patnaik MM, Roberts LR, Fernandez-Zapico ME. Carr RM, et al. Among authors: dhanasekaran r. J Biol Chem. 2020 Feb 28;295(9):2698-2712. doi: 10.1074/jbc.RA119.011146. Epub 2020 Jan 27. J Biol Chem. 2020. PMID: 31988246 Free PMC article.
Long-term clinical outcomes of patients with COVID-19 and chronic liver disease: US multicenter COLD study.
Aby ES, Moafa G, Latt N, Sultan MT, Cacioppo PA, Kumar S, Chung RT, Bloom PP, Gustafson J, Daidone M, Reinus Z, Debes JD, Sandhu S, Sohal A, Khalid S, Roytman M, Catana AM, Wegermann K, Carr RM, Saiman Y, Kassab I, Chen VL, Rabiee A, Rosenberg C, Nguyen V, Gainey C, Zhou K, Chavin K, Lizaola-Mayo BC, Chascsa DM, Varelas L, Moghe A, Dhanasekaran R. Aby ES, et al. Among authors: dhanasekaran r. Hepatol Commun. 2023 Jan 3;7(1):e8874. doi: 10.1097/01.HC9.0000897224.68874.de. eCollection 2023 Jan 1. Hepatol Commun. 2023. PMID: 36633476 Free PMC article.
Vasodilator-stimulated phosphoprotein promotes activation of hepatic stellate cells by regulating Rab11-dependent plasma membrane targeting of transforming growth factor beta receptors.
Tu K, Li J, Verma VK, Liu C, Billadeau DD, Lamprecht G, Xiang X, Guo L, Dhanasekaran R, Roberts LR, Shah VH, Kang N. Tu K, et al. Among authors: dhanasekaran r. Hepatology. 2015 Jan;61(1):361-74. doi: 10.1002/hep.27251. Epub 2014 Sep 19. Hepatology. 2015. PMID: 24917558 Free PMC article.
Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma.
Dhanasekaran R, Nakamura I, Hu C, Chen G, Oseini AM, Seven ES, Miamen AG, Moser CD, Zhou W, van Kuppevelt TH, van Deursen JM, Mounajjed T, Fernandez-Zapico ME, Roberts LR. Dhanasekaran R, et al. Hepatology. 2015 Apr;61(4):1269-83. doi: 10.1002/hep.27658. Epub 2015 Feb 13. Hepatology. 2015. PMID: 25503294 Free PMC article.
Transcriptional Induction of Periostin by a Sulfatase 2-TGFβ1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma.
Chen G, Nakamura I, Dhanasekaran R, Iguchi E, Tolosa EJ, Romecin PA, Vera RE, Almada LL, Miamen AG, Chaiteerakij R, Zhou M, Asiedu MK, Moser CD, Han S, Hu C, Banini BA, Oseini AM, Chen Y, Fang Y, Yang D, Shaleh HM, Wang S, Wu D, Song T, Lee JS, Thorgeirsson SS, Chevet E, Shah VH, Fernandez-Zapico ME, Roberts LR. Chen G, et al. Among authors: dhanasekaran r. Cancer Res. 2017 Feb 1;77(3):632-645. doi: 10.1158/0008-5472.CAN-15-2556. Epub 2016 Nov 21. Cancer Res. 2017. PMID: 27872089 Free PMC article.
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