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An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers.
Lee TK, Murthy SR, Cawley NX, Dhanvantari S, Hewitt SM, Lou H, Lau T, Ma S, Huynh T, Wesley RA, Ng IO, Pacak K, Poon RT, Loh YP. Lee TK, et al. Among authors: dhanvantari s. J Clin Invest. 2019 Mar 18;130(4):1804. doi: 10.1172/JCI128836. eCollection 2019 Mar 18. J Clin Invest. 2019. PMID: 30882370 Free PMC article. No abstract available.
Two dipolar α-helices within hormone-encoding regions of proglucagon are sorting signals to the regulated secretory pathway.
Guizzetti L, McGirr R, Dhanvantari S. Guizzetti L, et al. Among authors: dhanvantari s. J Biol Chem. 2014 May 23;289(21):14968-80. doi: 10.1074/jbc.M114.563684. Epub 2014 Apr 11. J Biol Chem. 2014. PMID: 24727476 Free PMC article.
Our previous work suggested that proglucagon is directed into granules by intrinsic sorting signals after initial processing to glicentin and major proglucagon fragment (McGirr, R., Guizzetti, L., and Dhanvantari, S. (2013) J. Endocrinol. 217, 229-240), leading to t …
Our previous work suggested that proglucagon is directed into granules by intrinsic sorting signals after initial processing to glicentin an …
50 results