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Long-Term Use of Proton Pump Inhibitors Disrupts Intestinal Tight Junction Barrier and Exaggerates Experimental Colitis.
Nighot M, Liao PL, Morris N, McCarthy D, Dharmaprakash V, Ullah Khan I, Dalessio S, Saha K, Ganapathy AS, Wang A, Ding W, Yochum G, Koltun W, Nighot P, Ma T. Nighot M, et al. Among authors: dharmaprakash v. J Crohns Colitis. 2023 Apr 19;17(4):565-579. doi: 10.1093/ecco-jcc/jjac168. J Crohns Colitis. 2023. PMID: 36322638 Free PMC article.
Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways.
Ganapathy AS, Saha K, Wang A, Arumugam P, Dharmaprakash V, Yochum G, Koltun W, Nighot M, Perdew G, Thompson TA, Ma T, Nighot P. Ganapathy AS, et al. Among authors: dharmaprakash v. Cell Rep. 2023 Jul 25;42(7):112705. doi: 10.1016/j.celrep.2023.112705. Epub 2023 Jun 30. Cell Rep. 2023. PMID: 37393618 Free PMC article.