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Epidermal growth factor pathway substrate 15, Eps15.
Salcini AE, Chen H, Iannolo G, De Camilli P, Di Fiore PP. Salcini AE, et al. Among authors: di fiore pp. Int J Biochem Cell Biol. 1999 Aug;31(8):805-9. doi: 10.1016/s1357-2725(99)00042-4. Int J Biochem Cell Biol. 1999. PMID: 10481267 Review.
The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.
Rosenthal JA, Chen H, Slepnev VI, Pellegrini L, Salcini AE, Di Fiore PP, De Camilli P. Rosenthal JA, et al. Among authors: di fiore pp. J Biol Chem. 1999 Nov 26;274(48):33959-65. doi: 10.1074/jbc.274.48.33959. J Biol Chem. 1999. PMID: 10567358
The interaction of epsin and Eps15 with the clathrin adaptor AP-2 is inhibited by mitotic phosphorylation and enhanced by stimulation-dependent dephosphorylation in nerve terminals.
Chen H, Slepnev VI, Di Fiore PP, De Camilli P. Chen H, et al. Among authors: di fiore pp. J Biol Chem. 1999 Feb 5;274(6):3257-60. doi: 10.1074/jbc.274.6.3257. J Biol Chem. 1999. PMID: 9920862
Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15.
Haffner C, Takei K, Chen H, Ringstad N, Hudson A, Butler MH, Salcini AE, Di Fiore PP, De Camilli P. Haffner C, et al. Among authors: di fiore pp. FEBS Lett. 1997 Dec 15;419(2-3):175-80. doi: 10.1016/s0014-5793(97)01451-8. FEBS Lett. 1997. PMID: 9428629
Eps15 is constitutively oligomerized due to homophilic interaction of its coiled-coil region.
Tebar F, Confalonieri S, Carter RE, Di Fiore PP, Sorkin A. Tebar F, et al. Among authors: di fiore pp. J Biol Chem. 1997 Jun 13;272(24):15413-8. doi: 10.1074/jbc.272.24.15413. J Biol Chem. 1997. PMID: 9182572
eps15 and eps15R are essential components of the endocytic pathway.
Carbone R, Fré S, Iannolo G, Belleudi F, Mancini P, Pelicci PG, Torrisi MR, Di Fiore PP. Carbone R, et al. Among authors: di fiore pp. Cancer Res. 1997 Dec 15;57(24):5498-504. Cancer Res. 1997. PMID: 9407958
Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF).
Hyman J, Chen H, Di Fiore PP, De Camilli P, Brunger AT. Hyman J, et al. Among authors: di fiore pp. J Cell Biol. 2000 May 1;149(3):537-46. doi: 10.1083/jcb.149.3.537. J Cell Biol. 2000. PMID: 10791968 Free PMC article.
Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis.
Confalonieri S, Salcini AE, Puri C, Tacchetti C, Di Fiore PP. Confalonieri S, et al. Among authors: di fiore pp. J Cell Biol. 2000 Aug 21;150(4):905-12. doi: 10.1083/jcb.150.4.905. J Cell Biol. 2000. PMID: 10953014 Free PMC article.
A JC virus-induced signal is required for infection of glial cells by a clathrin- and eps15-dependent pathway.
Querbes W, Benmerah A, Tosoni D, Di Fiore PP, Atwood WJ. Querbes W, et al. Among authors: di fiore pp. J Virol. 2004 Jan;78(1):250-6. doi: 10.1128/jvi.78.1.250-256.2004. J Virol. 2004. PMID: 14671106 Free PMC article.
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
Scita G, Tenca P, Frittoli E, Tocchetti A, Innocenti M, Giardina G, Di Fiore PP. Scita G, et al. Among authors: di fiore pp. EMBO J. 2000 Jun 1;19(11):2393-8. doi: 10.1093/emboj/19.11.2393. EMBO J. 2000. PMID: 10835338 Free PMC article. Review.
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