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Bridging solubility between drug discovery and development.
Di L, Fish PV, Mano T. Di L, et al. Drug Discov Today. 2012 May;17(9-10):486-95. doi: 10.1016/j.drudis.2011.11.007. Epub 2011 Nov 26. Drug Discov Today. 2012. PMID: 22138563 Review.
Stability challenges in drug discovery.
Di L, Kerns EH. Di L, et al. Chem Biodivers. 2009 Nov;6(11):1875-86. doi: 10.1002/cbdv.200900061. Chem Biodivers. 2009. PMID: 19937822
Applications of high throughput microsomal stability assay in drug discovery.
Di L, Kerns EH, Ma XJ, Huang Y, Carter GT. Di L, et al. Comb Chem High Throughput Screen. 2008 Jul;11(6):469-76. doi: 10.2174/138620708784911429. Comb Chem High Throughput Screen. 2008. PMID: 18673274
Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes.
McConnell O, Bach A 2nd, Balibar C, Byrne N, Cai Y, Carter G, Chlenov M, Di L, Fan K, Goljer I, He Y, Herold D, Kagan M, Kerns E, Koehn F, Kraml C, Marathias V, Marquez B, McDonald L, Nogle L, Petucci C, Schlingmann G, Tawa G, Tischler M, Williamson RT, Sutherland A, Watts W, Young M, Zhang MY, Zhang Y, Zhou D, Ho D. McConnell O, et al. Among authors: di l. Chirality. 2007 Sep;19(9):658-82. doi: 10.1002/chir.20399. Chirality. 2007. PMID: 17390370 Review.
Development of QSAR models for microsomal stability: identification of good and bad structural features for rat, human and mouse microsomal stability.
Hu Y, Unwalla R, Denny RA, Bikker J, Di L, Humblet C. Hu Y, et al. Among authors: di l. J Comput Aided Mol Des. 2010 Jan;24(1):23-35. doi: 10.1007/s10822-009-9309-9. Epub 2009 Nov 24. J Comput Aided Mol Des. 2010. PMID: 19937264
Drug-like property concepts in pharmaceutical design.
Di L, Kerns EH, Carter GT. Di L, et al. Curr Pharm Des. 2009;15(19):2184-94. doi: 10.2174/138161209788682479. Curr Pharm Des. 2009. PMID: 19601822 Review.
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