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Manganese effects on the human neuroblastoma cell line SK-ER3.
Di Lorenzo D, Ferrari F, Agrati P, de Vos H, Apostoli P, Alessio L, Albertini A, Maggi A. Di Lorenzo D, et al. Toxicol Appl Pharmacol. 1996 Sep;140(1):51-7. doi: 10.1006/taap.1996.0196. Toxicol Appl Pharmacol. 1996. PMID: 8806869
Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice.
Di Lorenzo D, Villa R, Biasiotto G, Belloli S, Ruggeri G, Albertini A, Apostoli P, Raviscioni M, Ciana P, Maggi A. Di Lorenzo D, et al. Endocrinology. 2002 Dec;143(12):4544-51. doi: 10.1210/en.2002-220448. Endocrinology. 2002. PMID: 12446581
Luciferase activity was also studied in 4-d-old mice lactating from a mother injected with either p,p'-DDT or o,p'-DDT. Both isomers induced a 2-fold increase in the newborn brain. ...
Luciferase activity was also studied in 4-d-old mice lactating from a mother injected with either p,p'-DDT or o,p'-DDT. Both isomers …
Whole body action of xenoestrogens with different chemical structures in estrogen reporter male mice.
Penza M, Bonetti E, Villa R, Ganzerla S, Bergonzi R, Biasiotto G, Caimi L, Apostoli P, Ciana P, Maggi A, Di Lorenzo D. Penza M, et al. Toxicology. 2004 Dec 1;205(1-2):65-73. doi: 10.1016/j.tox.2004.06.038. Toxicology. 2004. PMID: 15458791
Target-specific action of organochlorine compounds in reproductive and nonreproductive tissues of estrogen-reporter male mice.
Villa R, Bonetti E, Penza ML, Iacobello C, Bugari G, Bailo M, Parolini O, Apostoli P, Caimi L, Ciana P, Maggi A, Di Lorenzo D. Villa R, et al. Toxicol Appl Pharmacol. 2004 Dec 1;201(2):137-48. doi: 10.1016/j.taap.2004.05.007. Toxicol Appl Pharmacol. 2004. PMID: 15541753
Genistein affects adipose tissue deposition in a dose-dependent and gender-specific manner.
Penza M, Montani C, Romani A, Vignolini P, Pampaloni B, Tanini A, Brandi ML, Alonso-Magdalena P, Nadal A, Ottobrini L, Parolini O, Bignotti E, Calza S, Maggi A, Grigolato PG, Di Lorenzo D. Penza M, et al. Endocrinology. 2006 Dec;147(12):5740-51. doi: 10.1210/en.2006-0365. Epub 2006 Sep 7. Endocrinology. 2006. PMID: 16959845
Four-week-old C57BL/6 male and female mice received daily oral doses of genistein (50-200,000 microg/kg.d) or 17beta-estradiol (E2) (5 microg/kg.d) for 15 d or a diet containing 800 ppm genistein. ...The lower dose induced the phospholipase A2 group 7 and the …
Four-week-old C57BL/6 male and female mice received daily oral doses of genistein (50-200,000 microg/kg.d) or 17beta-estradiol (E2) ( …
Genistein accumulates in body depots and is mobilized during fasting, reaching estrogenic levels in serum that counter the hormonal actions of estradiol and organochlorines.
Penza M, Montani C, Romani A, Vignolini P, Ciana P, Maggi A, Pampaloni B, Caimi L, Di Lorenzo D. Penza M, et al. Toxicol Sci. 2007 Jun;97(2):299-307. doi: 10.1093/toxsci/kfm036. Epub 2007 Mar 3. Toxicol Sci. 2007. PMID: 17337754
Genistein is an efficient estrogen in the whole-body throughout mouse development.
Montani C, Penza M, Jeremic M, Biasiotto G, La Sala G, De Felici M, Ciana P, Maggi A, Di Lorenzo D. Montani C, et al. Toxicol Sci. 2008 May;103(1):57-67. doi: 10.1093/toxsci/kfn021. Epub 2008 Feb 14. Toxicol Sci. 2008. PMID: 18281260
Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?
Mazzoleni G, Di Lorenzo D, Steimberg N. Mazzoleni G, et al. Genes Nutr. 2009 Mar;4(1):13-22. doi: 10.1007/s12263-008-0107-0. Epub 2008 Dec 18. Genes Nutr. 2009. PMID: 19104883 Free PMC article.
Conventional studies based on two-dimensional (2-D) cell monolayers have demonstrated their significant limitations: the chemically and spatially defined three-dimensional (3-D) network of extracellular matrix components, cell-to-cell and cell-to-matrix interactions …
Conventional studies based on two-dimensional (2-D) cell monolayers have demonstrated their significant limitations: the chemically a …
Estrogen receptor-mediated transcriptional activity of genistein in the mouse testis.
Montani C, Penza M, Jeremic M, Rando G, Ciana P, Maggi A, La Sala G, De Felici M, Di Lorenzo D. Montani C, et al. Ann N Y Acad Sci. 2009 Apr;1163:475-7. doi: 10.1111/j.1749-6632.2008.03657.x. Ann N Y Acad Sci. 2009. PMID: 19456391
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