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Exosome-mediated communication in the ovarian follicle.
Di Pietro C. Di Pietro C. J Assist Reprod Genet. 2016 Mar;33(3):303-311. doi: 10.1007/s10815-016-0657-9. Epub 2016 Jan 27. J Assist Reprod Genet. 2016. PMID: 26814471 Free PMC article. Review.
Specific alterations of the microRNA transcriptome and global network structure in colorectal cancer after treatment with MAPK/ERK inhibitors.
Ragusa M, Statello L, Maugeri M, Majorana A, Barbagallo D, Salito L, Sammito M, Santonocito M, Angelica R, Cavallaro A, Scalia M, Caltabiano R, Privitera G, Biondi A, Di Vita M, Cappellani A, Vasquez E, Lanzafame S, Tendi E, Celeste S, Di Pietro C, Basile F, Purrello M. Ragusa M, et al. J Mol Med (Berl). 2012 Dec;90(12):1421-38. doi: 10.1007/s00109-012-0918-8. Epub 2012 Jun 4. J Mol Med (Berl). 2012. PMID: 22660396
SIRT1 signalling protects mouse oocytes against oxidative stress and is deregulated during aging.
Di Emidio G, Falone S, Vitti M, D'Alessandro AM, Vento M, Di Pietro C, Amicarelli F, Tatone C. Di Emidio G, et al. Hum Reprod. 2014 Sep;29(9):2006-17. doi: 10.1093/humrep/deu160. Epub 2014 Jun 24. Hum Reprod. 2014. PMID: 24963165
STUDY FUNDING/COMPETING INTERESTS: The work was supported by the Ministero dell'Università e della Ricerca Scientifica (MIUR) to C.T., F.A., C.D., A.M.D. ...
STUDY FUNDING/COMPETING INTERESTS: The work was supported by the Ministero dell'Università e della Ricerca Scientifica (MIUR) to C.T. …
Molecular characterization of exosomes and their microRNA cargo in human follicular fluid: bioinformatic analysis reveals that exosomal microRNAs control pathways involved in follicular maturation.
Santonocito M, Vento M, Guglielmino MR, Battaglia R, Wahlgren J, Ragusa M, Barbagallo D, Borzì P, Rizzari S, Maugeri M, Scollo P, Tatone C, Valadi H, Purrello M, Di Pietro C. Santonocito M, et al. Fertil Steril. 2014 Dec;102(6):1751-61.e1. doi: 10.1016/j.fertnstert.2014.08.005. Epub 2014 Sep 17. Fertil Steril. 2014. PMID: 25241362
miRNA profiling in vitreous humor, vitreal exosomes and serum from uveal melanoma patients: Pathological and diagnostic implications.
Ragusa M, Barbagallo C, Statello L, Caltabiano R, Russo A, Puzzo L, Avitabile T, Longo A, Toro MD, Barbagallo D, Valadi H, Di Pietro C, Purrello M, Reibaldi M. Ragusa M, et al. Cancer Biol Ther. 2015;16(9):1387-96. doi: 10.1080/15384047.2015.1046021. Epub 2015 May 7. Cancer Biol Ther. 2015. PMID: 25951497 Free PMC article.
Circulating miRNAs profiles in Tourette syndrome: molecular data and clinical implications.
Rizzo R, Ragusa M, Barbagallo C, Sammito M, Gulisano M, Calì PV, Pappalardo C, Barchitta M, Granata M, Condorelli AG, Barbagallo D, Scalia M, Agodi A, Di Pietro C, Purrello M. Rizzo R, et al. Mol Brain. 2015 Jul 25;8:44. doi: 10.1186/s13041-015-0133-y. Mol Brain. 2015. PMID: 26205656 Free PMC article.
Non-coding landscapes of colorectal cancer.
Ragusa M, Barbagallo C, Statello L, Condorelli AG, Battaglia R, Tamburello L, Barbagallo D, Di Pietro C, Purrello M. Ragusa M, et al. World J Gastroenterol. 2015 Nov 7;21(41):11709-39. doi: 10.3748/wjg.v21.i41.11709. World J Gastroenterol. 2015. PMID: 26556998 Free PMC article. Review.
MicroRNAs Are Stored in Human MII Oocyte and Their Expression Profile Changes in Reproductive Aging.
Battaglia R, Vento ME, Ragusa M, Barbagallo D, La Ferlita A, Di Emidio G, Borzí P, Artini PG, Scollo P, Tatone C, Purrello M, Di Pietro C. Battaglia R, et al. Biol Reprod. 2016 Dec;95(6):131. doi: 10.1095/biolreprod.116.142711. Epub 2016 Nov 9. Biol Reprod. 2016. PMID: 28007692
Non-coding RNAs in the Ovarian Follicle.
Battaglia R, Vento ME, Borzì P, Ragusa M, Barbagallo D, Arena D, Purrello M, Di Pietro C. Battaglia R, et al. Front Genet. 2017 May 12;8:57. doi: 10.3389/fgene.2017.00057. eCollection 2017. Front Genet. 2017. PMID: 28553318 Free PMC article.
Asymmetric RNA Distribution among Cells and Their Secreted Exosomes: Biomedical Meaning and Considerations on Diagnostic Applications.
Ragusa M, Barbagallo C, Cirnigliaro M, Battaglia R, Brex D, Caponnetto A, Barbagallo D, Di Pietro C, Purrello M. Ragusa M, et al. Front Mol Biosci. 2017 Oct 4;4:66. doi: 10.3389/fmolb.2017.00066. eCollection 2017. Front Mol Biosci. 2017. PMID: 29046875 Free PMC article. Review.
This phenomenon could depend both on passive and active sorting mechanisms related to: (a) RNA turnover; (b) maintaining the cytoplasmic miRNA:target equilibrium; (c) removal of RNAs not critical or even detrimental for normal or diseased cells. ...
This phenomenon could depend both on passive and active sorting mechanisms related to: (a) RNA turnover; (b) maintaining the cytoplasmic miR …
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