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The bone marrow: a nest for migratory memory T cells.
Di Rosa F, Pabst R. Di Rosa F, et al. Trends Immunol. 2005 Jul;26(7):360-6. doi: 10.1016/j.it.2005.04.011. Trends Immunol. 2005. PMID: 15978522 Review.
HLA class II molecules transduce accessory signals affecting the CD3 but not the interleukin-2 activation pathway in T blasts.
Di Rosa F, D'Oro U, Ruggiero G, Racioppi L, Acquaviva A, Ferrone S, Fontana S, Zappacosta S. Di Rosa F, et al. Hum Immunol. 1993 Dec;38(4):251-60. doi: 10.1016/0198-8859(93)90552-c. Hum Immunol. 1993. PMID: 8138420
On the lifespan of virgin T lymphocytes.
Di Rosa F, Ramaswamy S, Ridge JP, Matzinger P. Di Rosa F, et al. J Immunol. 1999 Aug 1;163(3):1253-7. J Immunol. 1999. PMID: 10415021
Bone marrow CD8 cells down-modulate membrane IL-7Ralpha expression and exhibit increased STAT-5 and p38 MAPK phosphorylation in the organ environment.
Cassese G, Parretta E, Pisapia L, Santoni A, Guardiola J, Di Rosa F. Cassese G, et al. Blood. 2007 Sep 15;110(6):1960-9. doi: 10.1182/blood-2006-09-045807. Epub 2007 May 17. Blood. 2007. PMID: 17510323
Phage display of a CTL epitope elicits a long-term in vivo cytotoxic response.
Mascolo D, Barba P, De Berardinis P, Di Rosa F, Del Pozzo G. Mascolo D, et al. FEMS Immunol Med Microbiol. 2007 Jun;50(1):59-66. doi: 10.1111/j.1574-695X.2007.00229.x. Epub 2007 Mar 28. FEMS Immunol Med Microbiol. 2007. PMID: 17391361 Free PMC article.
CD8 cell division maintaining cytotoxic memory occurs predominantly in the bone marrow.
Parretta E, Cassese G, Barba P, Santoni A, Guardiola J, Di Rosa F. Parretta E, et al. J Immunol. 2005 Jun 15;174(12):7654-64. doi: 10.4049/jimmunol.174.12.7654. J Immunol. 2005. PMID: 15944266
IL-15 inhibits IL-7Rα expression by memory-phenotype CD8⁺ T cells in the bone marrow.
Quinci AC, Vitale S, Parretta E, Soriani A, Iannitto ML, Cippitelli M, Fionda C, Bulfone-Paus S, Santoni A, Di Rosa F. Quinci AC, et al. Eur J Immunol. 2012 May;42(5):1129-39. doi: 10.1002/eji.201142019. Eur J Immunol. 2012. PMID: 22539288
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