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Page 1
Phospholipase Cε Modulates Rap1 Activity and the Endothelial Barrier.
DiStefano PV, Smrcka AV, Glading AJ. DiStefano PV, et al. PLoS One. 2016 Sep 9;11(9):e0162338. doi: 10.1371/journal.pone.0162338. eCollection 2016. PLoS One. 2016. PMID: 27612188 Free PMC article.
KRIT1 protein depletion modifies endothelial cell behavior via increased vascular endothelial growth factor (VEGF) signaling.
DiStefano PV, Kuebel JM, Sarelius IH, Glading AJ. DiStefano PV, et al. J Biol Chem. 2014 Nov 21;289(47):33054-65. doi: 10.1074/jbc.M114.582304. Epub 2014 Oct 15. J Biol Chem. 2014. PMID: 25320085 Free PMC article.
Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium.
Goitre L, DiStefano PV, Moglia A, Nobiletti N, Baldini E, Trabalzini L, Keubel J, Trapani E, Shuvaev VV, Muzykantov VR, Sarelius IH, Retta SF, Glading AJ. Goitre L, et al. Among authors: distefano pv. Sci Rep. 2017 Aug 15;7(1):8296. doi: 10.1038/s41598-017-08373-4. Sci Rep. 2017. PMID: 28811547 Free PMC article.
VEGF signalling enhances lesion burden in KRIT1 deficient mice.
DiStefano PV, Glading AJ. DiStefano PV, et al. J Cell Mol Med. 2020 Jan;24(1):632-639. doi: 10.1111/jcmm.14773. Epub 2019 Nov 20. J Cell Mol Med. 2020. PMID: 31746130 Free PMC article.
The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells.
Roy AR, Ahmed A, DiStefano PV, Chi L, Khyzha N, Galjart N, Wilson MD, Fish JE, Delgado-Olguín P. Roy AR, et al. Among authors: distefano pv. J Biol Chem. 2018 Jun 1;293(22):8449-8461. doi: 10.1074/jbc.M117.814699. Epub 2018 Apr 2. J Biol Chem. 2018. PMID: 29610276 Free PMC article.
Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling.
Fish JE, Flores Suarez CP, Boudreau E, Herman AM, Gutierrez MC, Gustafson D, DiStefano PV, Cui M, Chen Z, De Ruiz KB, Schexnayder TS, Ward CS, Radovanovic I, Wythe JD. Fish JE, et al. Among authors: distefano pv. Circ Res. 2020 Aug 28;127(6):727-743. doi: 10.1161/CIRCRESAHA.119.316500. Epub 2020 Jun 17. Circ Res. 2020. PMID: 32552404 Free PMC article.
Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain.
Nikolaev SI, Vetiska S, Bonilla X, Boudreau E, Jauhiainen S, Rezai Jahromi B, Khyzha N, DiStefano PV, Suutarinen S, Kiehl TR, Mendes Pereira V, Herman AM, Krings T, Andrade-Barazarte H, Tung T, Valiante T, Zadeh G, Tymianski M, Rauramaa T, Ylä-Herttuala S, Wythe JD, Antonarakis SE, Frösen J, Fish JE, Radovanovic I. Nikolaev SI, et al. Among authors: distefano pv. N Engl J Med. 2018 Jan 18;378(3):250-261. doi: 10.1056/NEJMoa1709449. Epub 2018 Jan 3. N Engl J Med. 2018. PMID: 29298116 Free article.
Mitochondrial ATP-sensitive potassium channel activity and hypoxic preconditioning are independent of an inwardly rectifying potassium channel subunit in Caenorhabditis elegans.
Wojtovich AP, DiStefano P, Sherman T, Brookes PS, Nehrke K. Wojtovich AP, et al. Among authors: distefano p. FEBS Lett. 2012 Feb 17;586(4):428-34. doi: 10.1016/j.febslet.2012.01.021. Epub 2012 Jan 21. FEBS Lett. 2012. PMID: 22281198 Free PMC article.
Cellular senescence contributes to age-dependent changes in circulating extracellular vesicle cargo and function.
Alibhai FJ, Lim F, Yeganeh A, DiStefano PV, Binesh-Marvasti T, Belfiore A, Wlodarek L, Gustafson D, Millar S, Li SH, Weisel RD, Fish JE, Li RK. Alibhai FJ, et al. Among authors: distefano pv. Aging Cell. 2020 Mar;19(3):e13103. doi: 10.1111/acel.13103. Epub 2020 Jan 21. Aging Cell. 2020. PMID: 31960578 Free PMC article.
Regulation of CCL2 expression in human vascular endothelial cells by a neighboring divergently transcribed long noncoding RNA.
Khyzha N, Khor M, DiStefano PV, Wang L, Matic L, Hedin U, Wilson MD, Maegdefessel L, Fish JE. Khyzha N, et al. Among authors: distefano pv. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16410-16419. doi: 10.1073/pnas.1904108116. Epub 2019 Jul 26. Proc Natl Acad Sci U S A. 2019. PMID: 31350345 Free PMC article.
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