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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
1985 1
1986 2
1987 6
1988 2
1989 3
1990 2
1991 1
1992 1
1993 6
1994 3
1995 2
1996 7
1997 9
1998 12
1999 5
2000 7
2001 15
2002 13
2003 6
2004 9
2005 11
2006 11
2007 9
2008 17
2009 12
2010 7
2011 10
2012 17
2013 9
2014 15
2015 27
2016 21
2017 25
2018 25
2019 18
2020 18
2021 36
2022 30
2023 38
2024 10

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438 results

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Page 1
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.
Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ. Liu X, et al. Br J Sports Med. 2018 Feb;52(3):167-175. doi: 10.1136/bjsports-2016-097333. Epub 2017 Oct 10. Br J Sports Med. 2018. PMID: 29018060 Review.
Another six (undenatured type II collagen, avocado soybean unsaponifiables, methylsulfonylmethane, diacerein, glucosamine and chondroitin) revealed statistically significant improvements on pain, but were of unclear clinical importance. ...There were no differences between …
Another six (undenatured type II collagen, avocado soybean unsaponifiables, methylsulfonylmethane, diacerein, glucosamine and chondro …
Current Treatment Options for Osteoarthritis.
Hermann W, Lambova S, Muller-Ladner U. Hermann W, et al. Curr Rheumatol Rev. 2018;14(2):108-116. doi: 10.2174/1573397113666170829155149. Curr Rheumatol Rev. 2018. PMID: 28875826 Review.
The standard pharmacological treatment includes agents for control of pain and inflammation (non-steroidal anti-inflammatory drugs, analgesics including opioids, intraarticular corticosteroids) and the group of the symptomatic slow acting drugs for OA such as glucosamine sulfate, …
The standard pharmacological treatment includes agents for control of pain and inflammation (non-steroidal anti-inflammatory drugs, analgesi …
Diacerein.
Spencer CM, Wilde MI. Spencer CM, et al. Drugs. 1997 Jan;53(1):98-106; discussion 107-8. doi: 10.2165/00003495-199753010-00007. Drugs. 1997. PMID: 9010651 Review.
Rhein, the active metabolite of diacerein, inhibits interleukin-1 activity. Consequently, collagenase production in articular cartilage is reduced. ...The predominant adverse effects of diacerein are diarrhoea and related disorders....
Rhein, the active metabolite of diacerein, inhibits interleukin-1 activity. Consequently, collagenase production in articular cartila …
Epidermolysis Bullosa Simplex.
So JY, Teng J. So JY, et al. 1998 Oct 7 [updated 2022 Aug 4]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 1998 Oct 7 [updated 2022 Aug 4]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301543 Free Books & Documents. Review.
In addition, botulinum toxin, cyproheptadine (Periactin()), tetracycline, erythromycin, diacerein, sirolimus, apremilast, cannabidiol oil, and gentamicin have all been reported to be beneficial. ...
In addition, botulinum toxin, cyproheptadine (Periactin()), tetracycline, erythromycin, diacerein, sirolimus, apremilast, cannabidiol …
Diacerein for osteoarthritis.
Fidelix TS, Macedo CR, Maxwell LJ, Fernandes Moça Trevisani V. Fidelix TS, et al. Cochrane Database Syst Rev. 2014 Feb 10;2014(2):CD005117. doi: 10.1002/14651858.CD005117.pub3. Cochrane Database Syst Rev. 2014. PMID: 24515444 Free PMC article. Review.
It has been proposed that diacerein acts as a slow-acting, symptom-modifying and perhaps disease-structure-modifying drug for OA. ...With respect to adverse effects of diacerein, diarrhoea was most frequent. Given the recent guidance issued by the EMA recommending s …
It has been proposed that diacerein acts as a slow-acting, symptom-modifying and perhaps disease-structure-modifying drug for OA. ... …
OARSI guidelines for the non-surgical management of knee osteoarthritis.
McAlindon TE, Bannuru RR, Sullivan MC, Arden NK, Berenbaum F, Bierma-Zeinstra SM, Hawker GA, Henrotin Y, Hunter DJ, Kawaguchi H, Kwoh K, Lohmander S, Rannou F, Roos EM, Underwood M. McAlindon TE, et al. Osteoarthritis Cartilage. 2014 Mar;22(3):363-88. doi: 10.1016/j.joca.2014.01.003. Epub 2014 Jan 24. Osteoarthritis Cartilage. 2014. PMID: 24462672 Free article.
Treatments of uncertain appropriateness for specific clinical sub-phenotypes included acupuncture, avocado soybean unsaponfiables, chondroitin, crutches, diacerein, glucosamine, intra-articular hyaluronic acid, opioids (oral and transdermal), rosehip, transcutaneous electr …
Treatments of uncertain appropriateness for specific clinical sub-phenotypes included acupuncture, avocado soybean unsaponfiables, chondroit …
Retraction.
[No authors listed] [No authors listed] Arthritis Rheumatol. 2023 Aug;75(8):1497. doi: 10.1002/art.42546. Epub 2023 Jun 20. Arthritis Rheumatol. 2023. PMID: 37337725
., Bohmova, J. and Rovensky, J. (2007), The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: A randomized, multicenter, double-blind, placebo-controlled study with primary end points at two months after the end of a three-month treat …
., Bohmova, J. and Rovensky, J. (2007), The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: …
Therapeutic Potential of Diacerein in Management of Pain.
Patel V, Joharapurkar A, Jain M. Patel V, et al. Curr Drug Res Rev. 2022;14(3):215-224. doi: 10.2174/2589977514666220428124623. Curr Drug Res Rev. 2022. PMID: 36281831 Review.
This review discusses the possible mechanism of diacerein in the management of pain. The potential role of rhein and diacerein in the treatment of neuropathic, inflammatory and nociceptive pain is also reviewed. ...The data highlights the role of diacerein in …
This review discusses the possible mechanism of diacerein in the management of pain. The potential role of rhein and diacerein
Expert opinion on emerging urate-lowering therapies.
Stamp LK, Merriman TR, Singh JA. Stamp LK, et al. Expert Opin Emerg Drugs. 2018 Sep;23(3):201-209. doi: 10.1080/14728214.2018.1527899. Expert Opin Emerg Drugs. 2018. PMID: 30244605 Review.
Areas covered: We review several new therapies for gout, including those that are focused on lowering serum urate (levotofisopam, ulodesine, verinurad, merbarone, KUX-1151, UR-1102, FYU-981, SEL-212), or treating gout flares (canakinumab, bucillamine) or both (arhalofenate, di
Areas covered: We review several new therapies for gout, including those that are focused on lowering serum urate (levotofisopam, ulodesine, …
Diacerein versus non-steroidal anti-inflammatory drugs in the treatment of knee osteoarthritis: a meta-analysis.
Zeng F, Wang K, Duan H, Xu XT, Kuang GY, Lu M. Zeng F, et al. J Orthop Surg Res. 2023 Apr 18;18(1):308. doi: 10.1186/s13018-023-03786-6. J Orthop Surg Res. 2023. PMID: 37072810 Free PMC article.
Emerging evidence suggests that the multifaceted symptomatology of KOA may be alleviated by diacerein. With this in mind, we conducted a systematic review and meta-analysis to evaluate the efficacy and safety of diacerein in patients with KOA. ...Moreover, there was …
Emerging evidence suggests that the multifaceted symptomatology of KOA may be alleviated by diacerein. With this in mind, we conducte …
438 results