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Identification of a dual δ OR antagonist/μ OR agonist as a potential therapeutic for diarrhea-predominant Irritable Bowel Syndrome (IBS-d).
Breslin HJ, Diamond CJ, Kavash RW, Cai C, Dyatkin AB, Miskowski TA, Zhang SP, Wade PR, Hornby PJ, He W. Breslin HJ, et al. Among authors: diamond cj. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4869-72. doi: 10.1016/j.bmcl.2012.05.042. Epub 2012 May 24. Bioorg Med Chem Lett. 2012. PMID: 22695132
Aza-bicyclic amino acid carboxamides as alpha4beta1/alpha4beta7 integrin receptor antagonists.
Dyatkin AB, Gong Y, Miskowski TA, Kimball ES, Prouty SM, Fisher MC, Santulli RJ, Schneider CR, Wallace NH, Hornby PJ, Diamond C, Kinney WA, Maryanoff BE, Damiano BP, He W. Dyatkin AB, et al. Bioorg Med Chem. 2005 Dec 15;13(24):6693-702. doi: 10.1016/j.bmc.2005.07.022. Epub 2005 Aug 19. Bioorg Med Chem. 2005. PMID: 16112583
Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-on e (TIBO) derivatives. 2.
Kukla MJ, Breslin HJ, Diamond CJ, Grous PP, Ho CY, Miranda M, Rodgers JD, Sherrill RG, De Clercq E, Pauwels R, et al. Kukla MJ, et al. Among authors: diamond cj. J Med Chem. 1991 Nov;34(11):3187-97. doi: 10.1021/jm00115a007. J Med Chem. 1991. PMID: 1956037
Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo-[4,5,1-jk][1,4]benzodiazepin- 2(1H)-one (TlBO) derivatives. 4.
Ho W, Kukla MJ, Breslin HJ, Ludovici DW, Grous PP, Diamond CJ, Miranda M, Rodgers JD, Ho CY, De Clercq E, et al. Ho W, et al. Among authors: diamond cj. J Med Chem. 1995 Mar 3;38(5):794-802. doi: 10.1021/jm00005a006. J Med Chem. 1995. PMID: 7877144
Efforts toward combined analgesic/antidepressants: synthesis and evaluation of (3-aryl-2,3-dihydrobenzofuran-3-yl)alkanamines.
Tegeler JJ, Diamond CJ, Wilker JC, Kruse H, Spaulding TC, Helsley GC. Tegeler JJ, et al. Among authors: diamond cj. J Pharm Sci. 1985 Jan;74(1):44-6. doi: 10.1002/jps.2600740112. J Pharm Sci. 1985. PMID: 3981416