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Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells.
Robino G, Parola M, Marra F, Caligiuri A, De Franco RM, Zamara E, Bellomo G, Gentilini P, Pinzani M, Dianzani MU. Robino G, et al. Among authors: dianzani mu. J Biol Chem. 2000 Dec 22;275(51):40561-7. doi: 10.1074/jbc.M007694200. J Biol Chem. 2000. PMID: 11007794 Free article.
Induction of procollagen type I gene expression and synthesis in human hepatic stellate cells by 4-hydroxy-2,3-nonenal and other 4-hydroxy-2,3-alkenals is related to their molecular structure.
Parola M, Pinzani M, Casini A, Leonarduzzi G, Marra F, Caligiuri A, Ceni E, Biondi P, Poli G, Dianzani MU. Parola M, et al. Among authors: dianzani mu. Biochem Biophys Res Commun. 1996 May 15;222(2):261-4. doi: 10.1006/bbrc.1996.0732. Biochem Biophys Res Commun. 1996. PMID: 8670193
HNE interacts directly with JNK isoforms in human hepatic stellate cells.
Parola M, Robino G, Marra F, Pinzani M, Bellomo G, Leonarduzzi G, Chiarugi P, Camandola S, Poli G, Waeg G, Gentilini P, Dianzani MU. Parola M, et al. Among authors: dianzani mu. J Clin Invest. 1998 Dec 1;102(11):1942-50. doi: 10.1172/JCI1413. J Clin Invest. 1998. PMID: 9835619 Free PMC article.
278 results