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Thermally activated TRP channels: molecular sensors for temperature detection.
Castillo K, Diaz-Franulic I, Canan J, Gonzalez-Nilo F, Latorre R. Castillo K, et al. Among authors: diaz franulic i. Phys Biol. 2018 Jan 24;15(2):021001. doi: 10.1088/1478-3975/aa9a6f. Phys Biol. 2018. PMID: 29135465 Review.
Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels.
Díaz-Franulic I, Sepúlveda RV, Navarro-Quezada N, González-Nilo F, Naranjo D. Díaz-Franulic I, et al. J Gen Physiol. 2015 Aug;146(2):133-46. doi: 10.1085/jgp.201411353. J Gen Physiol. 2015. PMID: 26216859 Free PMC article.
Effective pore size and radius of capture for K(+) ions in K-channels.
Moldenhauer H, Díaz-Franulic I, González-Nilo F, Naranjo D. Moldenhauer H, et al. Among authors: diaz franulic i. Sci Rep. 2016 Feb 2;6:19893. doi: 10.1038/srep19893. Sci Rep. 2016. PMID: 26831782 Free PMC article.
Allosterism and Structure in Thermally Activated Transient Receptor Potential Channels.
Diaz-Franulic I, Poblete H, Miño-Galaz G, González C, Latorre R. Diaz-Franulic I, et al. Annu Rev Biophys. 2016 Jul 5;45:371-98. doi: 10.1146/annurev-biophys-062215-011034. Epub 2016 May 23. Annu Rev Biophys. 2016. PMID: 27297398 Review.
Structure-Driven Pharmacology of Transient Receptor Potential Channel Vanilloid 1.
Díaz-Franulic I, Caceres-Molina J, Sepulveda RV, Gonzalez-Nilo F, Latorre R. Díaz-Franulic I, et al. Mol Pharmacol. 2016 Sep;90(3):300-8. doi: 10.1124/mol.116.104430. Epub 2016 Jun 22. Mol Pharmacol. 2016. PMID: 27335334 Review.
Pore size matters for potassium channel conductance.
Naranjo D, Moldenhauer H, Pincuntureo M, Díaz-Franulic I. Naranjo D, et al. Among authors: diaz franulic i. J Gen Physiol. 2016 Oct;148(4):277-91. doi: 10.1085/jgp.201611625. Epub 2016 Sep 12. J Gen Physiol. 2016. PMID: 27619418 Free PMC article. Review.
Gating-induced large aqueous volumetric remodeling and aspartate tolerance in the voltage sensor domain of Shaker K+ channels.
Díaz-Franulic I, González-Pérez V, Moldenhauer H, Navarro-Quezada N, Naranjo D. Díaz-Franulic I, et al. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8203-8208. doi: 10.1073/pnas.1806578115. Epub 2018 Jul 23. Proc Natl Acad Sci U S A. 2018. PMID: 30038023 Free PMC article.
A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels.
Díaz-Franulic I, Raddatz N, Castillo K, González-Nilo FD, Latorre R. Díaz-Franulic I, et al. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20298-20304. doi: 10.1073/pnas.2004303117. Epub 2020 Aug 3. Proc Natl Acad Sci U S A. 2020. PMID: 32747539
Novel TRPV1 Channel Agonists With Faster and More Potent Analgesic Properties Than Capsaicin.
Duarte Y, Cáceres J, Sepúlveda RV, Arriagada D, Olivares P, Díaz-Franulic I, Stehberg J, González-Nilo F. Duarte Y, et al. Among authors: diaz franulic i. Front Pharmacol. 2020 Jul 14;11:1040. doi: 10.3389/fphar.2020.01040. eCollection 2020. Front Pharmacol. 2020. PMID: 32760273 Free PMC article.
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