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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1920 1
1949 1
1955 1
1956 2
1957 1
1958 1
1959 1
1960 1
1962 1
1963 2
1964 2
1965 1
1966 2
1969 1
1970 2
1971 2
1976 1
1978 1
1980 2
1981 1
1982 2
1983 2
1985 2
1986 2
1988 2
1989 2
1990 2
1991 5
1992 3
1993 1
1994 4
1995 1
1996 4
1997 3
1998 5
1999 6
2000 3
2001 1
2002 4
2003 2
2004 2
2005 4
2006 4
2007 3
2008 5
2009 9
2010 14
2011 7
2012 6
2013 7
2014 4
2015 6
2016 3
2017 6
2018 7
2019 3
2020 5
2021 1
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Search Results

170 results
Results by year
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Page 1
A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.
Hyer ML, Milhollen MA, Ciavarri J, Fleming P, Traore T, Sappal D, Huck J, Shi J, Gavin J, Brownell J, Yang Y, Stringer B, Griffin R, Bruzzese F, Soucy T, Duffy J, Rabino C, Riceberg J, Hoar K, Lublinsky A, Menon S, Sintchak M, Bump N, Pulukuri SM, Langston S, Tirrell S, Kuranda M, Veiby P, Newcomb J, Li P, Wu JT, Powe J, Dick LR, Greenspan P, Galvin K, Manfredi M, Claiborne C, Amidon BS, Bence NF. Hyer ML, et al. Among authors: dick lr. Nat Med. 2018 Feb;24(2):186-193. doi: 10.1038/nm.4474. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334375
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.
Soucy TA, Smith PG, Milhollen MA, Berger AJ, Gavin JM, Adhikari S, Brownell JE, Burke KE, Cardin DP, Critchley S, Cullis CA, Doucette A, Garnsey JJ, Gaulin JL, Gershman RE, Lublinsky AR, McDonald A, Mizutani H, Narayanan U, Olhava EJ, Peluso S, Rezaei M, Sintchak MD, Talreja T, Thomas MP, Traore T, Vyskocil S, Weatherhead GS, Yu J, Zhang J, Dick LR, Claiborne CF, Rolfe M, Bolen JB, Langston SP. Soucy TA, et al. Among authors: dick lr. Nature. 2009 Apr 9;458(7239):732-6. doi: 10.1038/nature07884. Nature. 2009. PMID: 19360080
Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor.
He X, Riceberg J, Soucy T, Koenig E, Minissale J, Gallery M, Bernard H, Yang X, Liao H, Rabino C, Shah P, Xega K, Yan ZH, Sintchak M, Bradley J, Xu H, Duffey M, England D, Mizutani H, Hu Z, Guo J, Chau R, Dick LR, Brownell JE, Newcomb J, Langston S, Lightcap ES, Bence N, Pulukuri SM. He X, et al. Among authors: dick lr. Nat Chem Biol. 2017 Nov;13(11):1164-1171. doi: 10.1038/nchembio.2463. Epub 2017 Sep 11. Nat Chem Biol. 2017. PMID: 28892090
Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma.
Shirazi F, Jones RJ, Singh RK, Zou J, Kuiatse I, Berkova Z, Wang H, Lee HC, Hong S, Dick L, Chattopadhyay N, Orlowski RZ. Shirazi F, et al. Among authors: dick l. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20004-20014. doi: 10.1073/pnas.2005052117. Epub 2020 Aug 3. Proc Natl Acad Sci U S A. 2020. PMID: 32747568 Free PMC article.
Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer.
Kupperman E, Lee EC, Cao Y, Bannerman B, Fitzgerald M, Berger A, Yu J, Yang Y, Hales P, Bruzzese F, Liu J, Blank J, Garcia K, Tsu C, Dick L, Fleming P, Yu L, Manfredi M, Rolfe M, Bolen J. Kupperman E, et al. Among authors: dick l. Cancer Res. 2010 Mar 1;70(5):1970-80. doi: 10.1158/0008-5472.CAN-09-2766. Epub 2010 Feb 16. Cancer Res. 2010. PMID: 20160034 Free article.
The proteasome as a target for protozoan parasites.
Xie SC, Dick LR, Gould A, Brand S, Tilley L. Xie SC, et al. Among authors: dick lr. Expert Opin Ther Targets. 2019 Nov;23(11):903-914. doi: 10.1080/14728222.2019.1685981. Epub 2019 Nov 4. Expert Opin Ther Targets. 2019. PMID: 31679410 Review.
Coated microneedles for transdermal delivery of a potent pharmaceutical peptide.
Kapoor Y, Milewski M, Dick L, Zhang J, Bothe JR, Gehrt M, Manser K, Nissley B, Petrescu I, Johnson P, Burton S, Moseman J, Hua V, Grunewald T, Tomai M, Smith R. Kapoor Y, et al. Among authors: dick l. Biomed Microdevices. 2019 Dec 16;22(1):7. doi: 10.1007/s10544-019-0462-1. Biomed Microdevices. 2019. PMID: 31845070
170 results
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