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Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology.
Reardon B, Moore ND, Moore NS, Kofman E, AlDubayan SH, Cheung ATM, Conway J, Elmarakeby H, Imamovic A, Kamran SC, Keenan T, Keliher D, Konieczkowski DJ, Liu D, Mouw KW, Park J, Vokes NI, Dietlein F, Van Allen EM. Reardon B, et al. Among authors: dietlein f. Nat Cancer. 2021 Oct;2(10):1102-1112. doi: 10.1038/s43018-021-00243-3. Epub 2021 Sep 30. Nat Cancer. 2021. PMID: 35121878 Free PMC article.
Integrated molecular drivers coordinate biological and clinical states in melanoma.
Conway JR, Dietlein F, Taylor-Weiner A, AlDubayan S, Vokes N, Keenan T, Reardon B, He MX, Margolis CA, Weirather JL, Haq R, Schilling B, Stephen Hodi F, Schadendorf D, Liu D, Van Allen EM. Conway JR, et al. Among authors: dietlein f. Nat Genet. 2020 Dec;52(12):1373-1383. doi: 10.1038/s41588-020-00739-1. Epub 2020 Nov 23. Nat Genet. 2020. PMID: 33230298 Free PMC article.
Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.
Liu D, Schilling B, Liu D, Sucker A, Livingstone E, Jerby-Arnon L, Zimmer L, Gutzmer R, Satzger I, Loquai C, Grabbe S, Vokes N, Margolis CA, Conway J, He MX, Elmarakeby H, Dietlein F, Miao D, Tracy A, Gogas H, Goldinger SM, Utikal J, Blank CU, Rauschenberg R, von Bubnoff D, Krackhardt A, Weide B, Haferkamp S, Kiecker F, Izar B, Garraway L, Regev A, Flaherty K, Paschen A, Van Allen EM, Schadendorf D. Liu D, et al. Among authors: dietlein f. Nat Med. 2019 Dec;25(12):1916-1927. doi: 10.1038/s41591-019-0654-5. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792460 Free PMC article.
Identification of cancer driver genes based on nucleotide context.
Dietlein F, Weghorn D, Taylor-Weiner A, Richters A, Reardon B, Liu D, Lander ES, Van Allen EM, Sunyaev SR. Dietlein F, et al. Nat Genet. 2020 Feb;52(2):208-218. doi: 10.1038/s41588-019-0572-y. Epub 2020 Feb 3. Nat Genet. 2020. PMID: 32015527 Free PMC article.
Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival.
Gillani R, Seong BKA, Crowdis J, Conway JR, Dharia NV, Alimohamed S, Haas BJ, Han K, Park J, Dietlein F, He MX, Imamovic A, Ma C, Bassik MC, Boehm JS, Vazquez F, Gusev A, Liu D, Janeway KA, McFarland JM, Stegmaier K, Van Allen EM. Gillani R, et al. Among authors: dietlein f. Cancer Res. 2021 Aug 1;81(15):3971-3984. doi: 10.1158/0008-5472.CAN-21-0791. Epub 2021 Jun 7. Cancer Res. 2021. PMID: 34099491 Free PMC article.
Mutational Footprint of Platinum Chemotherapy in a Secondary Thyroid Cancer.
Schiantarelli J, Pappa T, Conway J, Crowdis J, Reardon B, Dietlein F, Huang J, Stanizzi D, Carey E, Bosma-Moody A, Imamovic A, Han S, Camp S, Kofman E, Shannon E, Barletta JA, He MX, Liu D, Park J, Lorch JH, Van Allen EM. Schiantarelli J, et al. Among authors: dietlein f. JCO Precis Oncol. 2022 Aug;6:e2200183. doi: 10.1200/PO.22.00183. JCO Precis Oncol. 2022. PMID: 36075011 Free PMC article. No abstract available.
Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.
Liu D, Schilling B, Liu D, Sucker A, Livingstone E, Jerby-Arnon L, Zimmer L, Gutzmer R, Satzger I, Loquai C, Grabbe S, Vokes N, Margolis CA, Conway J, He MX, Elmarakeby H, Dietlein F, Miao D, Tracy A, Gogas H, Goldinger SM, Utikal J, Blank CU, Rauschenberg R, von Bubnoff D, Krackhardt A, Weide B, Haferkamp S, Kiecker F, Izar B, Garraway L, Regev A, Flaherty K, Paschen A, Van Allen EM, Schadendorf D. Liu D, et al. Among authors: dietlein f. Nat Med. 2020 Jul;26(7):1147. doi: 10.1038/s41591-020-0975-4. Nat Med. 2020. PMID: 32561875 Free PMC article.
Harmonization of Tumor Mutational Burden Quantification and Association With Response to Immune Checkpoint Blockade in Non-Small-Cell Lung Cancer.
Vokes NI, Liu D, Ricciuti B, Jimenez-Aguilar E, Rizvi H, Dietlein F, He MX, Margolis CA, Elmarakeby HA, Girshman J, Adeni A, Sanchez-Vega F, Schultz N, Dahlberg S, Zehir A, Jänne PA, Nishino M, Umeton R, Sholl LM, Van Allen EM, Hellmann MD, Awad MM. Vokes NI, et al. Among authors: dietlein f. JCO Precis Oncol. 2019;3:PO.19.00171. doi: 10.1200/PO.19.00171. Epub 2019 Nov 12. JCO Precis Oncol. 2019. PMID: 31832578 Free PMC article.
Genome-wide analysis of somatic noncoding mutation patterns in cancer.
Dietlein F, Wang AB, Fagre C, Tang A, Besselink NJM, Cuppen E, Li C, Sunyaev SR, Neal JT, Van Allen EM. Dietlein F, et al. Science. 2022 Apr 8;376(6589):eabg5601. doi: 10.1126/science.abg5601. Epub 2022 Apr 8. Science. 2022. PMID: 35389777 Free PMC article.
Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas.
Derks S, de Klerk LK, Xu X, Fleitas T, Liu KX, Liu Y, Dietlein F, Margolis C, Chiaravalli AM, Da Silva AC, Ogino S, Akarca FG, Freeman GJ, Rodig SJ, Hornick JL, van Allen E, Li B, Liu SX, Thorsson V, Bass AJ. Derks S, et al. Among authors: dietlein f. Ann Oncol. 2020 Aug;31(8):1011-1020. doi: 10.1016/j.annonc.2020.04.011. Epub 2020 May 6. Ann Oncol. 2020. PMID: 32387455 Free PMC article.
36 results