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Year Number of Results
2003 1
2004 1
2005 1
2006 4
2007 3
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2012 1
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2014 2
2015 1
2016 3
2017 1
2018 3
2019 1
2020 1
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Differential activity of type I interferon subtypes for dendritic cell differentiation.
Garcin G, Bordat Y, Chuchana P, Monneron D, Law HK, Piehler J, Uzé G. Garcin G, et al. PLoS One. 2013;8(3):e58465. doi: 10.1371/journal.pone.0058465. Epub 2013 Mar 5. PLoS One. 2013. PMID: 23472200 Free PMC article.
Despite initial activation of the same Jak/Stat signalling pathway, the cellular response may differ depending on type I IFN subtype. We investigated the activity of six type I IFN subtypes - IFNalpha1, alpha2, alpha8, alpha21, omega and …
Despite initial activation of the same Jak/Stat signalling pathway, the cellular response may differ depending on type I IFN …
Differential type I interferon activation and susceptibility of dendritic cell populations to porcine arterivirus.
Loving CL, Brockmeier SL, Sacco RE. Loving CL, et al. Immunology. 2007 Feb;120(2):217-29. doi: 10.1111/j.1365-2567.2006.02493.x. Epub 2006 Nov 20. Immunology. 2007. PMID: 17116172 Free PMC article.
Dendritic cells (DCs) play a role in anti-viral immunity by providing early innate protection against viral replication and by presenting antigen to T cells for initiation of the adaptive immune response. ...Results show that PRRSV replicated in
Dendritic cells (DCs) play a role in anti-viral immunity by providing early innate protection against viral replication and by
Tissue-specific positive feedback requirements for production of type I interferon following virus infection.
Prakash A, Smith E, Lee CK, Levy DE. Prakash A, et al. J Biol Chem. 2005 May 13;280(19):18651-7. doi: 10.1074/jbc.M501289200. Epub 2005 Mar 14. J Biol Chem. 2005. PMID: 15767254 Free PMC article.
Type I interferon (IFN) is synthesized by most nucleated cells following viral infection. ...However, lymphoid tissue constitutively expressed high levels of IRF7 in the absence of induction or positive feedback, and this expression was largely confined to pl
Type I interferon (IFN) is synthesized by most nucleated cells following viral infection. ...However, lymphoid tissue c
Regulatory NLRs Control the RLR-Mediated Type I Interferon and Inflammatory Responses in Human Dendritic Cells.
Fekete T, Bencze D, Szabo A, Csoma E, Biro T, Bacsi A, Pazmandi K. Fekete T, et al. Front Immunol. 2018 Oct 5;9:2314. doi: 10.3389/fimmu.2018.02314. eCollection 2018. Front Immunol. 2018. PMID: 30344524 Free PMC article.
Unique members of the nucleotide-binding domain leucine-rich repeat (NLR) family have been found to regulate intracellular signaling pathways initiated by other families of pattern recognition receptors (PRR) such as Toll-like receptors (TLRs) and retinoic-acid inducible gene I ( …
Unique members of the nucleotide-binding domain leucine-rich repeat (NLR) family have been found to regulate intracellular signaling pathway …
Type I interferon: potential therapeutic target for psoriasis?
Yao Y, Richman L, Morehouse C, de los Reyes M, Higgs BW, Boutrin A, White B, Coyle A, Krueger J, Kiener PA, Jallal B. Yao Y, et al. PLoS One. 2008 Jul 16;3(7):e2737. doi: 10.1371/journal.pone.0002737. PLoS One. 2008. PMID: 18648529 Free PMC article.
METHODOLOGY/PRINCIPAL FINDINGS: We observed robust overexpression of type I interferon (IFN)-inducible genes and genomic signatures that indicate T cell and dendritic cell infiltration in lesional skin. ...Enrichment of mature dendritic
METHODOLOGY/PRINCIPAL FINDINGS: We observed robust overexpression of type I interferon (IFN)-inducible genes and genomic signa …
Interferon-alpha in the generation of monocyte-derived dendritic cells: recent advances and implications for dermatology.
Farkas A, Kemény L. Farkas A, et al. Br J Dermatol. 2011 Aug;165(2):247-54. doi: 10.1111/j.1365-2133.2011.10301.x. Epub 2011 Jun 2. Br J Dermatol. 2011. PMID: 21410666 Review.
Dendritic cells (DCs) have a critical role in antiviral responses, in autoimmune disease pathogenesis and in initiating and maintaining inflammatory skin disorders, and are candidates for cell-based immunotherapeutic approaches for tumours. Recent studies hav
Dendritic cells (DCs) have a critical role in antiviral responses, in autoimmune disease pathogenesis and in initiating and ma
Human pDCs display sex-specific differences in type I interferon subtypes and interferon alpha/beta receptor expression.
Ziegler SM, Beisel C, Sutter K, Griesbeck M, Hildebrandt H, Hagen SH, Dittmer U, Altfeld M. Ziegler SM, et al. Eur J Immunol. 2017 Feb;47(2):251-256. doi: 10.1002/eji.201646725. Epub 2017 Jan 3. Eur J Immunol. 2017. PMID: 27891600 Free article.
The outcomes of many diseases differ between women and men, with women experiencing a higher incidence and more severe pathogenesis of autoimmune and some infectious diseases. It has been suggested that this is partially due to activation of plasmacytoid dendritic
The outcomes of many diseases differ between women and men, with women experiencing a higher incidence and more severe pathogenesis of autoi …
Differential responses of plasmacytoid dendritic cells to influenza virus and distinct viral pathogens.
Thomas JM, Pos Z, Reinboth J, Wang RY, Wang E, Frank GM, Lusso P, Trinchieri G, Alter HJ, Marincola FM, Thomas E. Thomas JM, et al. J Virol. 2014 Sep;88(18):10758-66. doi: 10.1128/JVI.01501-14. Epub 2014 Jul 9. J Virol. 2014. PMID: 25008918 Free PMC article.
Plasmacytoid dendritic cells (pDCs) are key components of the innate immune response that are capable of synthesizing and rapidly releasing vast amounts of type I interferons (IFNs), particularly IFN-alpha. ...In addition, our data suggest that high-titer inf …
Plasmacytoid dendritic cells (pDCs) are key components of the innate immune response that are capable of synthesizing and rapi …
Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells.
Szabo A, Gogolak P, Koncz G, Foldvari Z, Pazmandi K, Miltner N, Poliska S, Bacsi A, Djurovic S, Rajnavolgyi E. Szabo A, et al. Sci Rep. 2018 Jan 29;8(1):1765. doi: 10.1038/s41598-018-20173-y. Sci Rep. 2018. PMID: 29379077 Free PMC article.
Serotonin is a monoamine neurotransmitter that signals through a wide array of receptors (5-HT(1-7)) many of which are also involved in immune processes. Dendritic cells (DCs) are crucial players in immune defense by bridging innate and adaptive immune responses via …
Serotonin is a monoamine neurotransmitter that signals through a wide array of receptors (5-HT(1-7)) many of which are also involved in immu …
Modification of TLR-induced activation of human dendritic cells by type I IFN: synergistic interaction with TLR4 but not TLR3 agonists.
Walker J, Tough DF. Walker J, et al. Eur J Immunol. 2006 Jul;36(7):1827-36. doi: 10.1002/eji.200635854. Eur J Immunol. 2006. PMID: 16783851 Free article.
Upon detection of direct and indirect signs of infection, dendritic cells (DC) undergo functional changes that modify their ability to elicit immune responses. Type I interferon (IFN-alpha/beta), which includes a large family of closely related infecti …
Upon detection of direct and indirect signs of infection, dendritic cells (DC) undergo functional changes that modify their ab …
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