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Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing.
Niehues T, von Hardenberg S, Velleuer E. Niehues T, et al. Allergol Select. 2024 Oct 2;8:304-323. doi: 10.5414/ALX02520E. eCollection 2024. Allergol Select. 2024. PMID: 39381601 Free PMC article.
They include a positive family history and/or signs of pathological susceptibility to infections, immunodysregulation, or syndromic disease. Results of conventional laboratory and most immunological lab studies are not sufficient to make a definitive diagnosis of PA …
They include a positive family history and/or signs of pathological susceptibility to infections, immunodysregulation, or syndromic …
Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death.
Toscano MA, Bianco GA, Ilarregui JM, Croci DO, Correale J, Hernandez JD, Zwirner NW, Poirier F, Riley EM, Baum LG, Rabinovich GA. Toscano MA, et al. Nat Immunol. 2007 Aug;8(8):825-34. doi: 10.1038/ni1482. Epub 2007 Jun 24. Nat Immunol. 2007. PMID: 17589510
Although TH1- and TH-17-differentiated cells expressed the repertoire of cell surface glycans critical for galectin-1-induced cell death, TH2 cells were protected from galectin-1 through differential sialylation of …
Although TH1- and TH-17-differentiated cells expressed the repertoire of cell surface glycans critical for galec …