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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1917 1
1945 2
1946 1
1947 2
1949 1
1950 1
1951 1
1952 2
1953 5
1954 5
1955 6
1956 6
1957 7
1958 5
1959 7
1960 8
1961 5
1962 6
1963 9
1964 21
1965 23
1966 47
1967 140
1968 353
1969 522
1970 372
1971 413
1972 331
1973 221
1974 367
1975 504
1976 339
1977 297
1978 227
1979 257
1980 258
1981 279
1982 248
1983 322
1984 296
1985 297
1986 267
1987 297
1988 267
1989 290
1990 259
1991 271
1992 298
1993 250
1994 257
1995 253
1996 248
1997 217
1998 209
1999 197
2000 211
2001 199
2002 187
2003 186
2004 218
2005 209
2006 187
2007 203
2008 245
2009 211
2010 220
2011 205
2012 278
2013 288
2014 253
2015 277
2016 333
2017 326
2018 340
2019 360
2020 368
2021 381
2022 385
2023 373
2024 406
2025 262

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16,050 results

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Page 1
Bidirectional Mendelian Randomization and Multiphenotype GWAS Show Causality and Shared Pathophysiology Between Depression and Type 2 Diabetes.
Maina JG, Balkhiyarova Z, Nouwen A, Pupko I, Ulrich A, Boissel M, Bonnefond A, Froguel P, Khamis A, Prokopenko I, Kaakinen M. Maina JG, et al. Diabetes Care. 2023 Sep 1;46(9):1707-1714. doi: 10.2337/dc22-2373. Diabetes Care. 2023. PMID: 37494602 Free PMC article.
RESEARCH DESIGN AND METHODS: We applied two-sample, bidirectional Mendelian randomization (MR) to assess causality between type 2 diabetes and depression. We investigated potential mediation using two-step MR. To identify shared genetics, we performed 1) genome-wide associ …
RESEARCH DESIGN AND METHODS: We applied two-sample, bidirectional Mendelian randomization (MR) to assess causality between type 2 diabetes a …
Inflammation: depression fans the flames and feasts on the heat.
Kiecolt-Glaser JK, Derry HM, Fagundes CP. Kiecolt-Glaser JK, et al. Am J Psychiatry. 2015 Nov 1;172(11):1075-91. doi: 10.1176/appi.ajp.2015.15020152. Epub 2015 Sep 11. Am J Psychiatry. 2015. PMID: 26357876 Free PMC article. Review.
Depression and inflammation fuel one another. Inflammation plays a key role in depression's pathogenesis for a subset of depressed individuals; depression also primes larger cytokine responses to stressors and pathogens that do not appear to hab …
Depression and inflammation fuel one another. Inflammation plays a key role in depression's pathogenesis for a subset o …
Fermented foods, the gut and mental health: a mechanistic overview with implications for depression and anxiety.
Aslam H, Green J, Jacka FN, Collier F, Berk M, Pasco J, Dawson SL. Aslam H, et al. Nutr Neurosci. 2020 Sep;23(9):659-671. doi: 10.1080/1028415X.2018.1544332. Epub 2018 Nov 11. Nutr Neurosci. 2020. PMID: 30415609 Review.
Mental disorders including depression and anxiety are often comorbid with gut problems, suggesting a bidirectional relationship between mental health and gut function. ...However, in humans, the literature relating to the relevance of fermented food for treating or prevent …
Mental disorders including depression and anxiety are often comorbid with gut problems, suggesting a bidirectional relationship betwe …
Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study.
Rudzki L, Ostrowska L, Pawlak D, Małus A, Pawlak K, Waszkiewicz N, Szulc A. Rudzki L, et al. Psychoneuroendocrinology. 2019 Feb;100:213-222. doi: 10.1016/j.psyneuen.2018.10.010. Epub 2018 Oct 16. Psychoneuroendocrinology. 2019. PMID: 30388595 Clinical Trial.
BACKGROUND: Interactions between the digestive system and the brain functions have become in recent years an important field of psychiatric research. ...The severity of psychiatric symptoms was assessed using Hamilton Depression Rating Scale (HAM-D 17), Sympt …
BACKGROUND: Interactions between the digestive system and the brain functions have become in recent years an important field o …
Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders: A Genome-Wide Pleiotropic Analysis.
Gong W, Guo P, Li Y, Liu L, Yan R, Liu S, Wang S, Xue F, Zhou X, Yuan Z. Gong W, et al. JAMA Psychiatry. 2023 Apr 1;80(4):360-370. doi: 10.1001/jamapsychiatry.2022.4974. JAMA Psychiatry. 2023. PMID: 36753304 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: This genome-wide pleiotropic association study using genome-wide association summary statistics from publicly available data sources was performed with various statistical genetic approaches to sequentially investigate the pleiotropic associatio …
DESIGN, SETTING, AND PARTICIPANTS: This genome-wide pleiotropic association study using genome-wide association summary statistics from publ …
GABA-modulating bacteria of the human gut microbiota.
Strandwitz P, Kim KH, Terekhova D, Liu JK, Sharma A, Levering J, McDonald D, Dietrich D, Ramadhar TR, Lekbua A, Mroue N, Liston C, Stewart EJ, Dubin MJ, Zengler K, Knight R, Gilbert JA, Clardy J, Lewis K. Strandwitz P, et al. Nat Microbiol. 2019 Mar;4(3):396-403. doi: 10.1038/s41564-018-0307-3. Epub 2018 Dec 10. Nat Microbiol. 2019. PMID: 30531975 Free PMC article.
The gut microbiota affects many important host functions, including the immune response and the nervous system(1). However, while substantial progress has been made in growing diverse microorganisms of the microbiota(2), 23-65% of species residing in the human gut remain u …
The gut microbiota affects many important host functions, including the immune response and the nervous system(1). However, while sub …
Increased global integration in the brain after psilocybin therapy for depression.
Daws RE, Timmermann C, Giribaldi B, Sexton JD, Wall MB, Erritzoe D, Roseman L, Nutt D, Carhart-Harris R. Daws RE, et al. Nat Med. 2022 Apr;28(4):844-851. doi: 10.1038/s41591-022-01744-z. Epub 2022 Apr 11. Nat Med. 2022. PMID: 35411074 Clinical Trial.
We assessed the subacute impact of psilocybin on brain function in two clinical trials of depression. The first was an open-label trial of orally administered psilocybin (10 mg and 25 mg, 7 d apart) in patients with treatment-resistant depression. ...Patients with m …
We assessed the subacute impact of psilocybin on brain function in two clinical trials of depression. The first was an open-label tri …
Gut microbiome and depression: what we know and what we need to know.
Winter G, Hart RA, Charlesworth RPG, Sharpley CF. Winter G, et al. Rev Neurosci. 2018 Aug 28;29(6):629-643. doi: 10.1515/revneuro-2017-0072. Rev Neurosci. 2018. PMID: 29397391 Review.
Gut microbiome diversity has been strongly associated with mood-relating behaviours, including major depressive disorder (MDD). This association stems from the recently characterised bi-directional communication system between the gut and the brain, mediated …
Gut microbiome diversity has been strongly associated with mood-relating behaviours, including major depressive disorder (MDD) …
Depression and anxiety management in cirrhosis.
Zimbrean PC, Jakab SS. Zimbrean PC, et al. Hepatol Commun. 2024 Dec 11;9(1):e0600. doi: 10.1097/HC9.0000000000000600. eCollection 2025 Jan 1. Hepatol Commun. 2024. PMID: 39670879 Free PMC article. Review.
Between 2009 and 2019, the prevalence of depression in cirrhosis increased by 80%, while the prevalence of generalized anxiety disorder increased by over 400%. ...Screening instruments for depression and anxiety have shown acceptable validity in patients with …
Between 2009 and 2019, the prevalence of depression in cirrhosis increased by 80%, while the prevalence of generalized anxiety dis …
16,050 results
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