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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1785 2
1794 1
1799 9
1800 13
1801 6
1802 2
1803 1
1804 2
1806 2
1808 5
1809 1
1815 1
1818 1
1822 1
1823 1
1824 1
1826 2
1827 1
1831 1
1832 1
1841 1
1842 1
1844 1
1845 2
1847 1
1853 1
1856 4
1857 1
1860 1
1861 5
1864 1
1865 1
1866 2
1868 4
1869 1
1870 1
1871 11
1872 4
1873 2
1874 4
1875 3
1876 4
1879 3
1880 2
1882 2
1884 4
1885 3
1886 1
1891 2
1892 4
1895 1
1896 1
1897 3
1899 1
1900 1
1902 1
1904 3
1905 1
1906 4
1907 2
1908 4
1909 2
1910 2
1911 4
1912 5
1914 1
1915 1
1916 2
1917 2
1918 2
1919 1
1920 1
1921 5
1922 3
1924 4
1925 4
1926 9
1927 5
1928 6
1929 6
1930 8
1931 1
1932 4
1933 3
1934 5
1935 4
1936 5
1937 2
1939 4
1940 3
1941 2
1942 3
1943 3
1944 1
1945 12
1946 56
1947 78
1948 92
1949 61
1950 108
1951 137
1952 119
1953 135
1954 139
1955 131
1956 128
1957 146
1958 135
1959 127
1960 124
1961 116
1962 154
1963 219
1964 369
1965 226
1966 191
1967 283
1968 291
1969 332
1970 360
1971 396
1972 372
1973 346
1974 333
1975 311
1976 318
1977 324
1978 282
1979 257
1980 242
1981 238
1982 265
1983 233
1984 281
1985 275
1986 260
1987 235
1988 217
1989 232
1990 202
1991 210
1992 213
1993 186
1994 148
1995 143
1996 140
1997 131
1998 125
1999 100
2000 117
2001 111
2002 106
2003 104
2004 96
2005 101
2006 99
2007 99
2008 79
2009 76
2010 79
2011 62
2012 85
2013 68
2014 63
2015 53
2016 56
2017 52
2018 62
2019 49
2020 56
2021 48
2022 54
2023 40
2024 43
2025 25

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13,260 results

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Page 1
The Foxgloves (Digitalis) Revisited.
Kreis W. Kreis W. Planta Med. 2017 Aug;83(12-13):962-976. doi: 10.1055/s-0043-111240. Epub 2017 May 23. Planta Med. 2017. PMID: 28561136 Free article. Review.
This review provides a renewed look at the genus Digitalis. Emphasis will be put on those issues that attracted the most attention or even went through paradigmatic changes since the turn of the millennium. PubMed and Google Scholar were used ("Digitalis" and "Foxgl …
This review provides a renewed look at the genus Digitalis. Emphasis will be put on those issues that attracted the most attention or …
[Digitalis poisonings].
HALBRON P. HALBRON P. Monde Med (Ed Esp). 1946 Jan-Feb;56:1-10. Monde Med (Ed Esp). 1946. PMID: 21022747 Spanish. No abstract available.
RNAi-mediated gene knockdown of progesterone 5beta-reductases in Digitalis lanata reduces 5beta-cardenolide content.
Klein J, Horn E, Ernst M, Leykauf T, Leupold T, Dorfner M, Wolf L, Ignatova A, Kreis W, Munkert J. Klein J, et al. Plant Cell Rep. 2021 Sep;40(9):1631-1646. doi: 10.1007/s00299-021-02707-3. Epub 2021 Jun 19. Plant Cell Rep. 2021. PMID: 34146141 Free PMC article.
Studying RNAi-mediated DlP5betaR1 and DlP5betaR2 knockdown shoot culture lines of Digitalis lanata, we here provide direct evidence for the participation of PRISEs (progesterone 5beta-reductase/iridoid synthase-like enzymes) in 5beta-cardenolide formation. ...Two PR …
Studying RNAi-mediated DlP5betaR1 and DlP5betaR2 knockdown shoot culture lines of Digitalis lanata, we here provide direct evi …
An Overview of Cardenolides in Digitalis - More Than a Cardiotonic Compound.
Gurel E, Karvar S, Yucesan B, Eker I, Sameeullah M. Gurel E, et al. Curr Pharm Des. 2017;23(34):5104-5114. doi: 10.2174/1381612823666170825125426. Curr Pharm Des. 2017. PMID: 28847302 Review.
Due to digoxigenin derivatives of cardenolides, which are mainly used for medicinal purposes, such as digoxigenin, D. lanata as a main source is of great interest for commercial scale production of cardenolides in Europe. ...During the last few decades, plant tissue cultur …
Due to digoxigenin derivatives of cardenolides, which are mainly used for medicinal purposes, such as digoxigenin, D. lanata as a mai …
Purification of delta(5)-3-ketosteroid isomerase from Digitalis lanata.
Meitinger N, Geiger D, Augusto TW, Maia de Pádua R, Kreis W. Meitinger N, et al. Phytochemistry. 2015 Jan;109:6-13. doi: 10.1016/j.phytochem.2014.10.025. Epub 2014 Nov 14. Phytochemistry. 2015. PMID: 25468533
It was shown that the delta(5)-3-ketosteroid isomerase of Digitalis lanata, which catalyzes this isomerization, is an individual enzyme and not, as previously thought, associated with delta(5)-3beta-hydroxysteroid dehydrogenase. ...
It was shown that the delta(5)-3-ketosteroid isomerase of Digitalis lanata, which catalyzes this isomerization, is an individu …
Overexpression and RNAi-mediated Knockdown of Two 3beta-hydroxy-delta5-steroid dehydrogenase Genes in Digitalis lanata Shoot Cultures Reveal Their Role in Cardenolide Biosynthesis.
Leykauf T, Klein J, Ernst M, Dorfner M, Ignatova A, Kreis W, Lanig H, Munkert J. Leykauf T, et al. Planta Med. 2023 Jul;89(8):833-847. doi: 10.1055/a-2074-9186. Epub 2023 May 15. Planta Med. 2023. PMID: 37187191
Here, a novel 3betaHSD (Dl3betaHSD2) was isolated from Digitalis lanata shoot cultures and expressed in E. coli. Recombinant Dl3betaHSD1 and Dl3betaHSD2 shared 70% amino acid identity, reduced various 3-oxopregnanes and oxidised 3-hydroxypregnanes, but only rDl3beta …
Here, a novel 3betaHSD (Dl3betaHSD2) was isolated from Digitalis lanata shoot cultures and expressed in E. coli. Recombinant D …
Cultivation and breeding of Digitalis lanata in the Netherlands.
Mastenbroek C. Mastenbroek C. Br Heart J. 1985 Sep;54(3):262-8. doi: 10.1136/hrt.54.3.262. Br Heart J. 1985. PMID: 4041298 Free PMC article.
After the second world war Marshall Aid funds were used to establish a cooperative organisation for growing, drying, and selling Digitalis lanata (and other medicinal, aromatic, and culinary herbs) in the Netherlands. ...
After the second world war Marshall Aid funds were used to establish a cooperative organisation for growing, drying, and selling Digitali …
Digitalis toxicity.
BULLOCH RT. BULLOCH RT. J Ark Med Soc. 1962 Feb;58:372-8. J Ark Med Soc. 1962. PMID: 13874616 No abstract available.
Digitalis therapy.
SCHERF D. SCHERF D. Dis Chest. 1958 Jan;33(1):93-8. doi: 10.1378/chest.33.1.93. Dis Chest. 1958. PMID: 13501092 No abstract available.
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