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Page 1
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: dillon kj. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967 Free article.
Phthalazinones 2: Optimisation and synthesis of novel potent inhibitors of poly(ADP-ribose)polymerase.
Cockcroft XL, Dillon KJ, Dixon L, Drzewiecki J, Kerrigan F, Loh VM Jr, Martin NM, Menear KA, Smith GC. Cockcroft XL, et al. Among authors: dillon kj. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1040-4. doi: 10.1016/j.bmcl.2005.10.081. Epub 2005 Nov 15. Bioorg Med Chem Lett. 2006. PMID: 16290932
4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.
Menear KA, Adcock C, Boulter R, Cockcroft XL, Copsey L, Cranston A, Dillon KJ, Drzewiecki J, Garman S, Gomez S, Javaid H, Kerrigan F, Knights C, Lau A, Loh VM Jr, Matthews IT, Moore S, O'Connor MJ, Smith GC, Martin NM. Menear KA, et al. Among authors: dillon kj. J Med Chem. 2008 Oct 23;51(20):6581-91. doi: 10.1021/jm8001263. Epub 2008 Sep 19. J Med Chem. 2008. PMID: 18800822
A FlashPlate assay for the identification of PARP-1 inhibitors.
Dillon KJ, Smith GC, Martin NM. Dillon KJ, et al. J Biomol Screen. 2003 Jun;8(3):347-52. doi: 10.1177/1087057103008003013. J Biomol Screen. 2003. PMID: 12857389
Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase.
Loh VM Jr, Cockcroft XL, Dillon KJ, Dixon L, Drzewiecki J, Eversley PJ, Gomez S, Hoare J, Kerrigan F, Matthews IT, Menear KA, Martin NM, Newton RF, Paul J, Smith GC, Vile J, Whittle AJ. Loh VM Jr, et al. Among authors: dillon kj. Bioorg Med Chem Lett. 2005 May 2;15(9):2235-8. doi: 10.1016/j.bmcl.2005.03.026. Bioorg Med Chem Lett. 2005. PMID: 15837300
Black Currant Nectar Reduces Muscle Damage and Inflammation Following a Bout of High-Intensity Eccentric Contractions.
Hutchison AT, Flieller EB, Dillon KJ, Leverett BD. Hutchison AT, et al. Among authors: dillon kj. J Diet Suppl. 2016;13(1):1-15. doi: 10.3109/19390211.2014.952864. Epub 2014 Aug 25. J Diet Suppl. 2016. PMID: 25153307 Clinical Trial.
Significant developments in stem cell research.
Dillon KJ. Dillon KJ. Hum Reprod Genet Ethics. 2006;12(1):24-8. doi: 10.1179/hrge.12.1.622747r1133787gj. Hum Reprod Genet Ethics. 2006. PMID: 17847634 No abstract available.