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Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin.
Wong WW, Tan MM, Xia Z, Dimitroulakos J, Minden MD, Penn LZ. Wong WW, et al. Among authors: dimitroulakos j. Clin Cancer Res. 2001 Jul;7(7):2067-75. Clin Cancer Res. 2001. PMID: 11448925
The statin family of drugs inhibits 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, the rate-limiting enzyme of the mevalonate pathway, and is used clinically as a safe and effective approach in the control of hypercholesterolemia. We have shown previously (Dimitroulakos
The statin family of drugs inhibits 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, the rate-limiting enzyme of the mevalonate pathway, …
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