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Pharmacological modulation of cholinergic brain activity and its reflection in special EEG frequency ranges from various brain areas in the freely moving rat (Tele-Stereo-EEG).
Dimpfel W. Dimpfel W. Eur Neuropsychopharmacol. 2005 Dec;15(6):673-82. doi: 10.1016/j.euroneuro.2005.03.006. Epub 2005 Jul 11. Eur Neuropsychopharmacol. 2005. PMID: 16009538
This special property of biperiden gives a plausible explanation for its efficacy in Parkinsonian patients since decreases of alpha2 waves in this model indicate enhancement of dopaminergic transmission [Dimpfel, W., Spuler, M., Koch, R., Schatton, W., 1987. …
This special property of biperiden gives a plausible explanation for its efficacy in Parkinsonian patients since decreases of alpha2 waves i …
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