Potentiometric sensing of butyrylcholinesterase based on in situ generation and detection of substrates

Chem Commun (Camb). 2009 Feb 28:(8):971-3. doi: 10.1039/b817064a. Epub 2008 Dec 19.

Abstract

A novel reagentless biosensor has been developed in which the traditional ion selective electrode is used as a controlled-release system for in situ generation and detection of enzyme substrates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques*
  • Butyrylcholinesterase / analysis*
  • Butyrylcholinesterase / chemistry
  • Choline / analogs & derivatives
  • Choline / chemistry
  • Pesticides / analysis*
  • Pesticides / chemistry
  • Potentiometry

Substances

  • Pesticides
  • butyrylcholine
  • Butyrylcholinesterase
  • Choline