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152 results
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Chemoprotection against cancer: an idea whose time has come.
Dinkova-Kostova AT. Dinkova-Kostova AT. Altern Ther Health Med. 2007 Mar-Apr;13(2):S122-7. Altern Ther Health Med. 2007. PMID: 17405689 Review. No abstract available.
Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen.
Dinkova-Kostova AT, Talalay P. Dinkova-Kostova AT, et al. Free Radic Biol Med. 2000 Aug;29(3-4):231-40. doi: 10.1016/s0891-5849(00)00300-2. Free Radic Biol Med. 2000. PMID: 11035251 Review.
Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans.
Ye L, Dinkova-Kostova AT, Wade KL, Zhang Y, Shapiro TA, Talalay P. Ye L, et al. Clin Chim Acta. 2002 Feb;316(1-2):43-53. doi: 10.1016/s0009-8981(01)00727-6. Clin Chim Acta. 2002. PMID: 11750273
Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane.
Gao X, Dinkova-Kostova AT, Talalay P. Gao X, et al. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15221-6. doi: 10.1073/pnas.261572998. Proc Natl Acad Sci U S A. 2001. PMID: 11752465 Free PMC article.
Protection against cancer by plant phenylpropenoids: induction of mammalian anticarcinogenic enzymes.
Dinkova-Kostova AT. Dinkova-Kostova AT. Mini Rev Med Chem. 2002 Dec;2(6):595-610. doi: 10.2174/1389557023405558. Mini Rev Med Chem. 2002. PMID: 12370043 Review.
Protection against electrophile and oxidative stress by induction of phase 2 genes: the quest for the elusive sensor that responds to inducers.
Holtzclaw WD, Dinkova-Kostova AT, Talalay P. Holtzclaw WD, et al. Adv Enzyme Regul. 2004;44:335-67. doi: 10.1016/j.advenzreg.2003.11.013. Adv Enzyme Regul. 2004. PMID: 15581500 Review. No abstract available.
Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts.
Dinkova-Kostova AT, Jenkins SN, Fahey JW, Ye L, Wehage SL, Liby KT, Stephenson KK, Wade KL, Talalay P. Dinkova-Kostova AT, et al. Cancer Lett. 2006 Aug 28;240(2):243-52. doi: 10.1016/j.canlet.2005.09.012. Epub 2005 Nov 3. Cancer Lett. 2006. PMID: 16271437
Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study.
Shapiro TA, Fahey JW, Dinkova-Kostova AT, Holtzclaw WD, Stephenson KK, Wade KL, Ye L, Talalay P. Shapiro TA, et al. Nutr Cancer. 2006;55(1):53-62. doi: 10.1207/s15327914nc5501_7. Nutr Cancer. 2006. PMID: 16965241 Clinical Trial.
Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast.
Cornblatt BS, Ye L, Dinkova-Kostova AT, Erb M, Fahey JW, Singh NK, Chen MS, Stierer T, Garrett-Mayer E, Argani P, Davidson NE, Talalay P, Kensler TW, Visvanathan K. Cornblatt BS, et al. Carcinogenesis. 2007 Jul;28(7):1485-90. doi: 10.1093/carcin/bgm049. Epub 2007 Mar 7. Carcinogenesis. 2007. PMID: 17347138
Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts.
Dinkova-Kostova AT, Fahey JW, Wade KL, Jenkins SN, Shapiro TA, Fuchs EJ, Kerns ML, Talalay P. Dinkova-Kostova AT, et al. Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):847-51. doi: 10.1158/1055-9965.EPI-06-0934. Cancer Epidemiol Biomarkers Prev. 2007. PMID: 17416783
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