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Chemoprotection against cancer by isothiocyanates: a focus on the animal models and the protective mechanisms.
Dinkova-Kostova AT. Dinkova-Kostova AT. Top Curr Chem. 2013;329:179-201. doi: 10.1007/128_2012_337. Top Curr Chem. 2013. PMID: 22752581 Review.
Chemoprotection against cancer: an idea whose time has come.
Dinkova-Kostova AT. Dinkova-Kostova AT. Altern Ther Health Med. 2007 Mar-Apr;13(2):S122-7. Altern Ther Health Med. 2007. PMID: 17405689 Review. No abstract available.
Direct and indirect antioxidant properties of inducers of cytoprotective proteins.
Dinkova-Kostova AT, Talalay P. Dinkova-Kostova AT, et al. Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S128-38. doi: 10.1002/mnfr.200700195. Mol Nutr Food Res. 2008. PMID: 18327872 Review.
Phytochemicals as protectors against ultraviolet radiation: versatility of effects and mechanisms.
Dinkova-Kostova AT. Dinkova-Kostova AT. Planta Med. 2008 Oct;74(13):1548-59. doi: 10.1055/s-2008-1081296. Epub 2008 Aug 11. Planta Med. 2008. PMID: 18696411 Review.
Cross-talk between transcription factors AhR and Nrf2: lessons for cancer chemoprevention from dioxin.
Hayes JD, Dinkova-Kostova AT, McMahon M. Hayes JD, et al. Toxicol Sci. 2009 Oct;111(2):199-201. doi: 10.1093/toxsci/kfp168. Epub 2009 Jul 23. Toxicol Sci. 2009. PMID: 19628587 No abstract available.
Activation of the NRF2 signaling pathway by copper-mediated redox cycling of para- and ortho-hydroquinones.
Wang XJ, Hayes JD, Higgins LG, Wolf CR, Dinkova-Kostova AT. Wang XJ, et al. Chem Biol. 2010 Jan 29;17(1):75-85. doi: 10.1016/j.chembiol.2009.12.013. Chem Biol. 2010. PMID: 20142043
Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice.
Dinkova-Kostova AT, Fahey JW, Benedict AL, Jenkins SN, Ye L, Wehage SL, Talalay P. Dinkova-Kostova AT, et al. Photochem Photobiol Sci. 2010 Apr;9(4):597-600. doi: 10.1039/b9pp00130a. Photochem Photobiol Sci. 2010. PMID: 20354656 Free PMC article.
Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway.
Hayes JD, McMahon M, Chowdhry S, Dinkova-Kostova AT. Hayes JD, et al. Antioxid Redox Signal. 2010 Dec 1;13(11):1713-48. doi: 10.1089/ars.2010.3221. Epub 2010 Aug 14. Antioxid Redox Signal. 2010. PMID: 20446772 Review.
An exceptionally potent inducer of cytoprotective enzymes: elucidation of the structural features that determine inducer potency and reactivity with Keap1.
Dinkova-Kostova AT, Talalay P, Sharkey J, Zhang Y, Holtzclaw WD, Wang XJ, David E, Schiavoni KH, Finlayson S, Mierke DF, Honda T. Dinkova-Kostova AT, et al. J Biol Chem. 2010 Oct 29;285(44):33747-55. doi: 10.1074/jbc.M110.163485. Epub 2010 Aug 26. J Biol Chem. 2010. PMID: 20801881 Free PMC article.
Induction of the Keap1/Nrf2/ARE pathway by oxidizable diphenols.
Dinkova-Kostova AT, Wang XJ. Dinkova-Kostova AT, et al. Chem Biol Interact. 2011 Jun 30;192(1-2):101-6. doi: 10.1016/j.cbi.2010.09.010. Epub 2010 Sep 21. Chem Biol Interact. 2011. PMID: 20846517
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