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Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer.
Tucker DW, Getchell CR, McCarthy ET, Ohman AW, Sasamoto N, Xu S, Ko JY, Gupta M, Shafrir A, Medina JE, Lee JJ, MacDonald LA, Malik A, Hasselblatt KT, Li W, Zhang H, Kaplan SJ, Murphy GF, Hirsch MS, Liu JF, Matulonis UA, Terry KL, Lian CG, Dinulescu DM. Tucker DW, et al. Among authors: dinulescu dm. Clin Cancer Res. 2018 Mar 15;24(6):1389-1401. doi: 10.1158/1078-0432.CCR-17-1958. Epub 2017 Dec 20. Clin Cancer Res. 2018. PMID: 29263182 Free PMC article.
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy.
McAuliffe SM, Morgan SL, Wyant GA, Tran LT, Muto KW, Chen YS, Chin KT, Partridge JC, Poole BB, Cheng KH, Daggett J Jr, Cullen K, Kantoff E, Hasselbatt K, Berkowitz J, Muto MG, Berkowitz RS, Aster JC, Matulonis UA, Dinulescu DM. McAuliffe SM, et al. Among authors: dinulescu dm. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):E2939-48. doi: 10.1073/pnas.1206400109. Epub 2012 Sep 27. Proc Natl Acad Sci U S A. 2012. PMID: 23019585 Free PMC article.
Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.
Perets R, Wyant GA, Muto KW, Bijron JG, Poole BB, Chin KT, Chen JY, Ohman AW, Stepule CD, Kwak S, Karst AM, Hirsch MS, Setlur SR, Crum CP, Dinulescu DM, Drapkin R. Perets R, et al. Among authors: dinulescu dm. Cancer Cell. 2013 Dec 9;24(6):751-65. doi: 10.1016/j.ccr.2013.10.013. Cancer Cell. 2013. PMID: 24332043 Free PMC article.
Targeting platinum resistant disease in ovarian cancer.
Morgan SL, Medina JE, Taylor MM, Dinulescu DM. Morgan SL, et al. Among authors: dinulescu dm. Curr Med Chem. 2014;21(26):3009-20. doi: 10.2174/0929867321666140414102701. Curr Med Chem. 2014. PMID: 24735363
The promise and challenge of ovarian cancer models.
Hasan N, Ohman AW, Dinulescu DM. Hasan N, et al. Among authors: dinulescu dm. Transl Cancer Res. 2015 Feb;4(1):14-28. doi: 10.3978/j.issn.2218-676X.2015.01.02. Transl Cancer Res. 2015. PMID: 26114093 Free PMC article.
46 results