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Page 1
Anticancer Activity of Diosgenin and Its Molecular Mechanism.
Ren QL, Wang Q, Zhang XQ, Wang M, Hu H, Tang JJ, Yang XT, Ran YH, Liu HH, Song ZX, Liu JG, Li XL. Ren QL, et al. Chin J Integr Med. 2023 Aug;29(8):738-749. doi: 10.1007/s11655-023-3693-1. Epub 2023 Mar 20. Chin J Integr Med. 2023. PMID: 36940072 Free PMC article. Review.
Diosgenin, a steroidal sapogenin, obtained from Trigonella foenum-graecum, Dioscorea, and Rhizoma polgonati, has shown high potential and interest in the treatment of various cancers such as oral squamous cell carcinoma, laryngeal cancer, esophageal cancer, liver cancer, g …
Diosgenin, a steroidal sapogenin, obtained from Trigonella foenum-graecum, Dioscorea, and Rhizoma polgonati, has shown high potential …
Anticancer Potential of the Plant-Derived Saponin Gracillin: A Comprehensive Review of Mechanistic Approaches.
Bhuia MS, Chowdhury R, Sonia FA, Kamli H, Shaikh A, El-Nashar HAS, El-Shazly M, Islam MT. Bhuia MS, et al. Chem Biodivers. 2023 Sep;20(9):e202300847. doi: 10.1002/cbdv.202300847. Epub 2023 Aug 31. Chem Biodivers. 2023. PMID: 37547969 Review.
Gracillin is a naturally occurring triterpenoid steroidal saponin with several therapeutic activities. It is obtained as a major compound from different Dioscorea species. This review was designated to summarize the research progress on the anti-cancer activities of gracil …
Gracillin is a naturally occurring triterpenoid steroidal saponin with several therapeutic activities. It is obtained as a major compound fr …
Protective effect of Di'ao Xinxuekang capsule against doxorubicin-induced chronic cardiotoxicity.
Li X, Liang J, Qin A, Wang T, Liu S, Li W, Yuan C, Qu L, Zou W. Li X, et al. J Ethnopharmacol. 2022 Apr 6;287:114943. doi: 10.1016/j.jep.2021.114943. Epub 2021 Dec 24. J Ethnopharmacol. 2022. PMID: 34954266
ETHNOPHARMACOLOGICAL RELEVANCE: Di'ao Xinxuekang capsule (DXXK) extracted from Dioscorea nipponica Makino is a well-known traditional Chinese herbal medicinal product widely used in the treatment of cardiovascular disease, such as myocardial ischemia and arrhythmia. ...Mor …
ETHNOPHARMACOLOGICAL RELEVANCE: Di'ao Xinxuekang capsule (DXXK) extracted from Dioscorea nipponica Makino is a well-known traditional …
Novel platinum-palladium bimetallic nanoparticles synthesized by Dioscorea bulbifera: anticancer and antioxidant activities.
Ghosh S, Nitnavare R, Dewle A, Tomar GB, Chippalkatti R, More P, Kitture R, Kale S, Bellare J, Chopade BA. Ghosh S, et al. Int J Nanomedicine. 2015 Dec 17;10:7477-90. doi: 10.2147/IJN.S91579. eCollection 2015. Int J Nanomedicine. 2015. PMID: 26719690 Free PMC article.
Herein, we report for the first time the rapid efficient synthesis of novel platinum-palladium bimetallic nanoparticles (Pt-PdNPs) along with individual platinum (PtNPs) and palladium (PdNPs) nanoparticles using a medicinal plant, Dioscorea bulbifera tuber extract (DBTE). …
Herein, we report for the first time the rapid efficient synthesis of novel platinum-palladium bimetallic nanoparticles (Pt-PdNPs) along wit …
The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro.
Aumsuwan P, Khan SI, Khan IA, Ali Z, Avula B, Walker LA, Shariat-Madar Z, Helferich WG, Katzenellenbogen BS, Dasmahapatra AK. Aumsuwan P, et al. Arch Biochem Biophys. 2016 Feb 1;591:98-110. doi: 10.1016/j.abb.2015.12.001. Epub 2015 Dec 10. Arch Biochem Biophys. 2016. PMID: 26682631
Previously, we observed that wild yam (Dioscorea villosa) root extract (WYRE) was able to activate GATA3 in human breast cancer cells targeting epigenome. ...
Previously, we observed that wild yam (Dioscorea villosa) root extract (WYRE) was able to activate GATA3 in human breast cancer cells …
Effects of diosgenin and its derivatives on atherosclerosis.
Wu FC, Jiang JG. Wu FC, et al. Food Funct. 2019 Nov 1;10(11):7022-7036. doi: 10.1039/c9fo00749k. Epub 2019 Nov 5. Food Funct. 2019. PMID: 31687707 Review.
More and more studies have reported that DSG has significant pharmacological activities such as anticancer, cardiovascular protection, hypolipidemic, anti-inflammatory, and neuroprotection. ...
More and more studies have reported that DSG has significant pharmacological activities such as anticancer, cardiovascular protection …
Antimetastatic Potentials of Dioscorea nipponica on Melanoma In Vitro and In Vivo.
Ho ML, Hsieh YS, Chen JY, Chen KS, Chen JJ, Kuo WH, Lin SJ, Chen PN. Ho ML, et al. Evid Based Complement Alternat Med. 2011;2011:507920. doi: 10.1155/2011/507920. Epub 2011 Jan 10. Evid Based Complement Alternat Med. 2011. PMID: 21274459 Free PMC article.
Recent studies have revealed pleiotropic anticancer and antiproliferative capabilities of Dioscorea nipponica Makino whereas the effect of this plant on metastasis of cancer cells has not been clearly clarified. In the present study, we extracted Dioscorea ni …
Recent studies have revealed pleiotropic anticancer and antiproliferative capabilities of Dioscorea nipponica Makino whereas t …
Red mold dioscorea-induced G2/M arrest and apoptosis in human oral cancer cells.
Hsu WH, Lee BH, Pan TM. Hsu WH, et al. J Sci Food Agric. 2010 Dec;90(15):2709-15. doi: 10.1002/jsfa.4144. J Sci Food Agric. 2010. PMID: 20812379
BACKGROUND: Monascus-fermented products are among the most commonly used traditional food supplements. Dioscorea is known to exhibit anticancer properties. In this study the effects of the ethanol extract of red mold dioscorea (RMDE) on cell proliferation, ce …
BACKGROUND: Monascus-fermented products are among the most commonly used traditional food supplements. Dioscorea is known to exhibit …
Diosgenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 4)-beta-D-glucopyranoside obtained as a new anticancer agent from Dioscorea futschauensis induces apoptosis on human colon carcinoma HCT-15 cells via mitochondria-controlled apoptotic pathway.
Wang SL, Cai B, Cui CB, Liu HW, Wu CF, Yao XS. Wang SL, et al. J Asian Nat Prod Res. 2004 Jun;6(2):115-25. doi: 10.1080/1028602031000147357. J Asian Nat Prod Res. 2004. PMID: 15008458
Diosgenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 4)-beta-D-glucopyranoside (DRG) is a well-known pentacyclic triterpene glycoside newly isolated from the rhizomes of Dioscorea futschauensis R. Kunth (Dioscoreaceae) by our group. In the present work, the inhibitory effect of …
Diosgenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 4)-beta-D-glucopyranoside (DRG) is a well-known pentacyclic triterpene glycoside newly isola …
Molecular Changes Following Induction of Hepatocellular Carcinoma by Diethylnitrosamine and Thioacetamide, and Subsequent Treatment with Dioscorea membranacea Extract.
Kerdput V, Kanjanapongkul K, Itharat A, Pramong R, Lamers WH, Hakvoort TBM, Jongejan A, Pradidarcheep W. Kerdput V, et al. Int J Med Sci. 2022 Oct 9;19(12):1806-1815. doi: 10.7150/ijms.72987. eCollection 2022. Int J Med Sci. 2022. PMID: 36313224 Free PMC article.
Hepatocellular carcinoma (HCC) is a primary liver cancer commonly found in adults. Previously, we showed the anticancer effects of Thai herbal plant extract, Dioscorea membranacea Pierre (DM), in HCC-bearing rats. ...
Hepatocellular carcinoma (HCC) is a primary liver cancer commonly found in adults. Previously, we showed the anticancer effects of Th …
53 results