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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
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2007 4
2008 4
2009 2
2010 7
2011 10
2012 16
2013 21
2014 22
2015 37
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2017 94
2018 147
2019 151
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1,423 results

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Page 1
Development and Validation of the DOAC Score: A Novel Bleeding Risk Prediction Tool for Patients With Atrial Fibrillation on Direct-Acting Oral Anticoagulants.
Aggarwal R, Ruff CT, Virdone S, Perreault S, Kakkar AK, Palazzolo MG, Dorais M, Kayani G, Singer DE, Secemsky E, Piccini J, Tahir UA, Shen C, Yeh RW. Aggarwal R, et al. Circulation. 2023 Sep 19;148(12):936-946. doi: 10.1161/CIRCULATIONAHA.123.064556. Epub 2023 Aug 25. Circulation. 2023. PMID: 37621213 Free PMC article.
This study develops and validates a clinical risk score to personalize estimates of bleeding risk for individuals with atrial fibrillation taking direct-acting oral anticoagulants (DOACs). ...The primary outcome was major bleeding. The risk score …
This study develops and validates a clinical risk score to personalize estimates of bleeding risk for individuals with atrial fibrill …
Venous thromboembolism.
Khan F, Tritschler T, Kahn SR, Rodger MA. Khan F, et al. Lancet. 2021 Jul 3;398(10294):64-77. doi: 10.1016/S0140-6736(20)32658-1. Epub 2021 May 10. Lancet. 2021. PMID: 33984268 Review.
Diagnosis requires a sequential work-up that combines assessment of clinical pretest probability for venous thromboembolism using a clinical score (eg, Wells score), D-dimer testing, and imaging. Venous thromboembolism can be considered excluded in patients with bot …
Diagnosis requires a sequential work-up that combines assessment of clinical pretest probability for venous thromboembolism using a clinical …
Pulmonary embolism: update on management and controversies.
Duffett L, Castellucci LA, Forgie MA. Duffett L, et al. BMJ. 2020 Aug 5;370:m2177. doi: 10.1136/bmj.m2177. BMJ. 2020. PMID: 32759284 Review.
The use of either clinical probability adjusted or age adjusted D-dimer interpretation has led to a reduction in diagnostic imaging to exclude pulmonary embolism. Direct oral anticoagulation therapies are safe, effective, and convenient treatments for most pa …
The use of either clinical probability adjusted or age adjusted D-dimer interpretation has led to a reduction in diagnostic imaging to exclu …
Acute pulmonary embolism.
Howard L. Howard L. Clin Med (Lond). 2019 May;19(3):243-247. doi: 10.7861/clinmedicine.19-3-247. Clin Med (Lond). 2019. PMID: 31092519 Free PMC article. Review.
Pulmonary embolism response teams are on the increase to provide advice in such cases. Direct oral anticoagulants have been a major advance in treatment this decade, but are not appropriate for all patients. Follow-up of patients with pulmonary embolism shoul …
Pulmonary embolism response teams are on the increase to provide advice in such cases. Direct oral anticoagulants have …
Atrial fibrillation and stroke: State-of-the-art and future directions.
Elsheikh S, Hill A, Irving G, Lip GYH, Abdul-Rahim AH. Elsheikh S, et al. Curr Probl Cardiol. 2024 Jan;49(1 Pt C):102181. doi: 10.1016/j.cpcardiol.2023.102181. Epub 2023 Oct 31. Curr Probl Cardiol. 2024. PMID: 37913929 Free article. Review.
There are also ongoing debates on the management of acute stroke in patients with AF, and those who experienced breakthrough stroke while on oral anticoagulants. We provided an overview of the complex interplay between AF and stroke, as well as the treatment and sec …
There are also ongoing debates on the management of acute stroke in patients with AF, and those who experienced breakthrough stroke while on …
Association of Alternative Anticoagulation Strategies and Outcomes in Patients With Ischemic Stroke While Taking a Direct Oral Anticoagulant.
Ip YMB, Lau KK, Ko H, Lau L, Yao A, Wong GL, Yip TC, Leng X, Chan H, Chan H, Mok V, Soo YOY, Seiffge D, Leung TW. Ip YMB, et al. Neurology. 2023 Jul 25;101(4):e358-e369. doi: 10.1212/WNL.0000000000207422. Epub 2023 May 24. Neurology. 2023. PMID: 37225430 Free PMC article.
BACKGROUND AND OBJECTIVES: Ischemic stroke despite a direct oral anticoagulant (DOAC) is increasingly common and portends a high risk of subsequent ischemic stroke. ...We aimed to compare the outcomes of patients with ischemic stroke despite DOACs with and wi …
BACKGROUND AND OBJECTIVES: Ischemic stroke despite a direct oral anticoagulant (DOAC) is increasingly common and porten …
Stroke and thromboembolism prevention in atrial fibrillation.
Jame S, Barnes G. Jame S, et al. Heart. 2020 Jan;106(1):10-17. doi: 10.1136/heartjnl-2019-314898. Epub 2019 Sep 18. Heart. 2020. PMID: 31533990 Free PMC article. Review.
Once at-risk patients are identified, vitamin K antagonists (VKAs) and, more recently, direct oral anticoagulants (DOACs) are the primary medical therapy for stroke prevention. ...Some controversy exists regarding anticoagulation management for cardiov …
Once at-risk patients are identified, vitamin K antagonists (VKAs) and, more recently, direct oral anticoagulants (DOAC …
Reduction of Upper Gastrointestinal Bleeding Risk With Proton Pump Inhibitor Therapy in Asian Patients With Atrial Fibrillation Receiving Direct Oral Anticoagulant: A Nationwide Population-based Cohort Study.
Lee SR, Ahn HJ, Choi EK, Park SH, Han KD, Oh S, Lip GYH. Lee SR, et al. Clin Gastroenterol Hepatol. 2024 May;22(5):981-993.e11. doi: 10.1016/j.cgh.2023.12.022. Epub 2024 Jan 4. Clin Gastroenterol Hepatol. 2024. PMID: 38184099
BACKGROUND & AIMS: In patients with atrial fibrillation (AF) receiving direct oral anticoagulant (DOAC), upper gastrointestinal bleeding (UGIB) is a serious complication. ...RESULTS: A total of 165,624 patients were included (mean age: 72.2 10.8 years; me …
BACKGROUND & AIMS: In patients with atrial fibrillation (AF) receiving direct oral anticoagulant (DOAC), upper gast …
Emergency medicine updates: Atrial fibrillation with rapid ventricular response.
Long B, Brady WJ, Gottlieb M. Long B, et al. Am J Emerg Med. 2023 Dec;74:57-64. doi: 10.1016/j.ajem.2023.09.012. Epub 2023 Sep 18. Am J Emerg Med. 2023. PMID: 37776840 Review.
Rate control using beta blockers or calcium channel blockers should be pursued in those with AF with RVR who do not undergo cardioversion. Anticoagulation is an important component of management, and several tools (e.g., CHA(2)DS(2)-VASc) are available to assist with this …
Rate control using beta blockers or calcium channel blockers should be pursued in those with AF with RVR who do not undergo cardioversion. …
Association Between Use of Pharmacokinetic-Interacting Drugs and Effectiveness and Safety of Direct Acting Oral Anticoagulants: Nested Case-Control Study.
Gronich N, Stein N, Muszkat M. Gronich N, et al. Clin Pharmacol Ther. 2021 Dec;110(6):1526-1536. doi: 10.1002/cpt.2369. Epub 2021 Aug 10. Clin Pharmacol Ther. 2021. PMID: 34287842 Free PMC article.
Concomitant use of direct oral anticoagulants (DOACs) and medications with inhibition/induction effect on P-gp/CYP3A might increase risk of bleeding/treatment failure, respectively. We designed a nested case-control study within a Clalit cohort of patients wi …
Concomitant use of direct oral anticoagulants (DOACs) and medications with inhibition/induction effect on P-gp/CYP3A mi …
1,423 results