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Regulation of fetal gene expression in heart failure.
Dirkx E, da Costa Martins PA, De Windt LJ. Dirkx E, et al. Biochim Biophys Acta. 2013 Dec;1832(12):2414-24. doi: 10.1016/j.bbadis.2013.07.023. Epub 2013 Sep 10. Biochim Biophys Acta. 2013. PMID: 24036209 Review.
MicroRNA 214 Is a Potential Regulator of Thyroid Hormone Levels in the Mouse Heart Following Myocardial Infarction, by Targeting the Thyroid-Hormone-Inactivating Enzyme Deiodinase Type III.
Janssen R, Zuidwijk MJ, Muller A, van Mil A, Dirkx E, Oudejans CB, Paulus WJ, Simonides WS. Janssen R, et al. Among authors: dirkx e. Front Endocrinol (Lausanne). 2016 Mar 9;7:22. doi: 10.3389/fendo.2016.00022. eCollection 2016. Front Endocrinol (Lausanne). 2016. PMID: 27014189 Free PMC article.
Antisense MicroRNA Therapeutics in Cardiovascular Disease: Quo Vadis?
Philippen LE, Dirkx E, Wit JB, Burggraaf K, de Windt LJ, da Costa Martins PA. Philippen LE, et al. Among authors: dirkx e. Mol Ther. 2015 Dec;23(12):1810-8. doi: 10.1038/mt.2015.133. Epub 2015 Jul 28. Mol Ther. 2015. PMID: 26216517 Free PMC article. Review.
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure.
Dirkx E, Gladka MM, Philippen LE, Armand AS, Kinet V, Leptidis S, El Azzouzi H, Salic K, Bourajjaj M, da Silva GJ, Olieslagers S, van der Nagel R, de Weger R, Bitsch N, Kisters N, Seyen S, Morikawa Y, Chanoine C, Heymans S, Volders PG, Thum T, Dimmeler S, Cserjesi P, Eschenhagen T, da Costa Martins PA, De Windt LJ. Dirkx E, et al. Nat Cell Biol. 2013 Nov;15(11):1282-93. doi: 10.1038/ncb2866. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161931
The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation.
el Azzouzi H, Leptidis S, Dirkx E, Hoeks J, van Bree B, Brand K, McClellan EA, Poels E, Sluimer JC, van den Hoogenhof MM, Armand AS, Yin X, Langley S, Bourajjaj M, Olieslagers S, Krishnan J, Vooijs M, Kurihara H, Stubbs A, Pinto YM, Krek W, Mayr M, da Costa Martins PA, Schrauwen P, De Windt LJ. el Azzouzi H, et al. Among authors: dirkx e. Cell Metab. 2013 Sep 3;18(3):341-54. doi: 10.1016/j.cmet.2013.08.009. Cell Metab. 2013. PMID: 24011070
Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure.
Raso A, Dirkx E, Philippen LE, Fernandez-Celis A, De Majo F, Sampaio-Pinto V, Sansonetti M, Juni R, El Azzouzi H, Calore M, Bitsch N, Olieslagers S, Oerlemans MIFJ, Huibers MM, de Weger RA, Reckman YJ, Pinto YM, Zentilin L, Zacchigna S, Giacca M, da Costa Martins PA, López-Andrés N, De Windt LJ. Raso A, et al. Among authors: dirkx e. Mol Ther. 2019 Mar 6;27(3):584-599. doi: 10.1016/j.ymthe.2018.11.011. Epub 2018 Nov 17. Mol Ther. 2019. PMID: 30559069 Free PMC article.
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