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Increased extracellular K+ concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression-like depolarizations and spreading ischemia.
Petzold GC, Windmüller O, Haack S, Major S, Buchheim K, Megow D, Gabriel S, Lehmann TN, Drenckhahn C, Peters O, Meierkord H, Heinemann U, Dirnagl U, Dreier JP. Petzold GC, et al. Among authors: dirnagl u. Stroke. 2005 Jun;36(6):1270-7. doi: 10.1161/01.STR.0000166023.51307.e0. Epub 2005 May 5. Stroke. 2005. PMID: 15879337
Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage.
Dreier JP, Major S, Manning A, Woitzik J, Drenckhahn C, Steinbrink J, Tolias C, Oliveira-Ferreira AI, Fabricius M, Hartings JA, Vajkoczy P, Lauritzen M, Dirnagl U, Bohner G, Strong AJ; COSBID study group. Dreier JP, et al. Among authors: dirnagl u. Brain. 2009 Jul;132(Pt 7):1866-81. doi: 10.1093/brain/awp102. Epub 2009 May 6. Brain. 2009. PMID: 19420089 Free PMC article.
Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state.
Mergenthaler P, Kahl A, Kamitz A, van Laak V, Stohlmann K, Thomsen S, Klawitter H, Przesdzing I, Neeb L, Freyer D, Priller J, Collins TJ, Megow D, Dirnagl U, Andrews DW, Meisel A. Mergenthaler P, et al. Among authors: dirnagl u. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1518-23. doi: 10.1073/pnas.1108225109. Epub 2012 Jan 10. Proc Natl Acad Sci U S A. 2012. PMID: 22233811 Free PMC article.
388 results