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Opening a can of worms in AL progression.
Dispenzieri A. Dispenzieri A. Blood. 2018 Feb 1;131(5):475-476. doi: 10.1182/blood-2017-11-815423. Blood. 2018. PMID: 29437606 No abstract available.
Eligibility for hematopoietic stem-cell transplantation for primary systemic amyloidosis is a favorable prognostic factor for survival.
Dispenzieri A, Lacy MQ, Kyle RA, Therneau TM, Larson DR, Rajkumar SV, Fonseca R, Greipp PR, Witzig TE, Lust JA, Gertz MA. Dispenzieri A, et al. J Clin Oncol. 2001 Jul 15;19(14):3350-6. doi: 10.1200/JCO.2001.19.14.3350. J Clin Oncol. 2001. PMID: 11454882
This article addresses the extent to which eligibility to undergo HSCT is a favorable prognostic feature and explores prognostic factors within the subset of eligible patients. ...A randomized trial is needed to assess the true effect of HSCT....
This article addresses the extent to which eligibility to undergo HSCT is a favorable prognostic feature and explores prognostic fact …
Early lymphocyte recovery predicts superior survival after autologous hematopoietic stem cell transplantation in multiple myeloma or non-Hodgkin lymphoma.
Porrata LF, Gertz MA, Inwards DJ, Litzow MR, Lacy MQ, Tefferi A, Gastineau DA, Dispenzieri A, Ansell SM, Micallef IN, Geyer SM, Markovic SN. Porrata LF, et al. Among authors: dispenzieri a. Blood. 2001 Aug 1;98(3):579-85. doi: 10.1182/blood.v98.3.579. Blood. 2001. PMID: 11468153
Lower relapse rates seen in allogeneic stem cell transplantation have been related to early absolute lymphocyte count (ALC) recovery as a manifestation of early graft-verus-tumor effect. ...This is a retrospective study of patients with MM and NHL who underwent ASCT …
Lower relapse rates seen in allogeneic stem cell transplantation have been related to early absolute lymphocyte count (ALC) recovery as a
Translocations involving the immunoglobulin heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosis.
Hayman SR, Bailey RJ, Jalal SM, Ahmann GJ, Dispenzieri A, Gertz MA, Greipp PR, Kyle RA, Lacy MQ, Rajkumar SV, Witzig TE, Lust JA, Fonseca R. Hayman SR, et al. Among authors: dispenzieri a. Blood. 2001 Oct 1;98(7):2266-8. doi: 10.1182/blood.v98.7.2266. Blood. 2001. PMID: 11568015
Primary systemic amyloidosis (AL) is a plasma cell (PC) dyscrasia with clinical similarities to multiple myeloma (MM) and monoclonal gammopathy of undetermined significance (MGUS), but its molecular basis is poorly understood. ...Of 29 patients studied, 21 (72.4%) showed r …
Primary systemic amyloidosis (AL) is a plasma cell (PC) dyscrasia with clinical similarities to multiple myeloma (MM) and monoclonal …
Troponin levels in patients with amyloid cardiomyopathy undergoing cardiac transplantation.
Miller WL, Wright RS, McGregor CG, Dispenzieri A, McConnell JP, Burritt MF, Jaffe AS. Miller WL, et al. Among authors: dispenzieri a. Am J Cardiol. 2001 Oct 1;88(7):813-5. doi: 10.1016/s0002-9149(01)01877-x. Am J Cardiol. 2001. PMID: 11589859 No abstract available.
Immunoglobulin light chain amyloidosis and the kidney.
Gertz MA, Lacy MQ, Dispenzieri A. Gertz MA, et al. Among authors: dispenzieri a. Kidney Int. 2002 Jan;61(1):1-9. doi: 10.1046/j.1523-1755.2002.00085.x. Kidney Int. 2002. PMID: 11786079 Review.
Amyloidosis (AL) is a common cause of nephrotic syndrome in nondiabetic, nonhypertensive adults. All adult patients with nephrotic syndrome should have immunofixation of serum and urine as a screen. The finding of a monoclonal protein, particularly of lambda …
Amyloidosis (AL) is a common cause of nephrotic syndrome in nondiabetic, nonhypertensive adults. All adult patients with nephrotic sy …
Deletions of 17p13.1 and 13q14 are uncommon in Waldenström macroglobulinemia clonal cells and mostly seen at the time of disease progression.
Schop RF, Jalal SM, Van Wier SA, Ahmann GJ, Bailey RJ, Kyle RA, Greipp PR, Rajkumar SV, Gertz MA, Lust JA, Lacy MQ, Dispenzieri A, Witzig TE, Fonseca R. Schop RF, et al. Among authors: dispenzieri a. Cancer Genet Cytogenet. 2002 Jan 1;132(1):55-60. doi: 10.1016/s0165-4608(01)00526-x. Cancer Genet Cytogenet. 2002. PMID: 11801310
Waldenström macroglobulinemia (WM) is a plasma cell dyscrasia characterized by a monoclonal IgM paraproteinemia. Deletions of 17p13.1 and 13q14 are associated with tumor progression and worsened outcome in multiple myeloma (MM), and we thus investigated WM patients …
Waldenström macroglobulinemia (WM) is a plasma cell dyscrasia characterized by a monoclonal IgM paraproteinemia. Deletions of …
A multicenter phase II trial of 4'-iodo-4'deoxydoxorubicin (IDOX) in primary amyloidosis (AL).
Gertz MA, Lacy MQ, Dispenzieri A, Cheson BD, Barlogie B, Kyle RA, Palladini G, Geyer SM, Merlini G. Gertz MA, et al. Among authors: dispenzieri a. Amyloid. 2002 Mar;9(1):24-30. doi: 10.3109/13506120209072441. Amyloid. 2002. PMID: 12000194 Clinical Trial.
A multicenter study attempted to develop a dosing schedule to confirm those results. METHODS: Patients with biopsy-proven amyloidosis were required to have a cardiac ejection fraction > 50%, ventricular septal thickness < 20 mm, serum creatinine < 2.
A multicenter study attempted to develop a dosing schedule to confirm those results. METHODS: Patients with biopsy-proven amyl
Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis.
Rajkumar SV, Mesa RA, Fonseca R, Schroeder G, Plevak MF, Dispenzieri A, Lacy MQ, Lust JA, Witzig TE, Gertz MA, Kyle RA, Russell SJ, Greipp PR. Rajkumar SV, et al. Among authors: dispenzieri a. Clin Cancer Res. 2002 Jul;8(7):2210-6. Clin Cancer Res. 2002. PMID: 12114422
BM angiogenesis was studied in a blinded manner by immunohistochemical staining for CD34 to identify microvessels. RESULTS: The median (range) microvessel density (MVD) per x400 high power field was 1.3 (0-11) in the controls, 1.7 (0-10) in AL, 3 (0-23) in MGUS, 4 (1-30) i …
BM angiogenesis was studied in a blinded manner by immunohistochemical staining for CD34 to identify microvessels. RESULTS: The media …
Prognostic value of angiogenesis in solitary bone plasmacytoma.
Kumar S, Fonseca R, Dispenzieri A, Lacy MQ, Lust JA, Wellik L, Witzig TE, Gertz MA, Kyle RA, Greipp PR, Rajkumar SV. Kumar S, et al. Among authors: dispenzieri a. Blood. 2003 Mar 1;101(5):1715-7. doi: 10.1182/blood-2002-08-2441. Epub 2002 Oct 17. Blood. 2003. PMID: 12393501
Solitary plasmacytoma is a localized plasma cell malignancy that progresses to MM in a significant number of patients. We examined if angiogenesis is increased in solitary plasmacytoma and if it can help identify patients likely to progress to myeloma. ...Angiogenes …
Solitary plasmacytoma is a localized plasma cell malignancy that progresses to MM in a significant number of patients. We exam …
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