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Distinct Gene Regulatory Pathways for Human Innate versus Adaptive Lymphoid Cells.
Koues OI, Collins PL, Cella M, Robinette ML, Porter SI, Pyfrom SC, Payton JE, Colonna M, Oltz EM. Koues OI, et al. Cell. 2016 May 19;165(5):1134-1146. doi: 10.1016/j.cell.2016.04.014. Epub 2016 May 5. Cell. 2016. PMID: 27156452 Free PMC article.
Innate lymphoid cells (ILCs) serve as sentinels in mucosal tissues, sensing release of soluble inflammatory mediators, rapidly communicating danger via cytokine secretion, and functioning as guardians of tissue homeostasis. ...Here, we report gene r …
Innate lymphoid cells (ILCs) serve as sentinels in mucosal tissues, sensing release of soluble inflammatory mediators, …
Prediabetes uncovers differential gene expression at fasting and in response to oral glucose load in immune cells.
Mallu ACT, Vasudevan M, Allanki S, Nathan AA, Ravi MM, Ramanathan GS, Pradeepa R, Mohan V, Dixit M. Mallu ACT, et al. Clin Nutr. 2021 Mar;40(3):1247-1259. doi: 10.1016/j.clnu.2020.08.007. Epub 2020 Aug 13. Clin Nutr. 2021. PMID: 32863060
RESULTS: Glucose load specifically altered the expression of 112 genes in NGT and 356 genes in PD subjects. Biological significance analysis revealed transient up-regulation of innate and adaptive immune response related genes following oral glu …
RESULTS: Glucose load specifically altered the expression of 112 genes in NGT and 356 genes in PD subjects. Biological signifi …
Transcriptomic analysis of vitamin D responses in uterine and peripheral NK cells.
Tamblyn JA, Jeffery LE, Susarla R, Lissauer DM, Coort SL, Garcia AM, Knoblich K, Fletcher AL, Bulmer JN, Kilby MD, Hewison M. Tamblyn JA, et al. Reproduction. 2019 Aug;158(2):211-221. doi: 10.1530/REP-18-0509. Reproduction. 2019. PMID: 31163399 Free PMC article.
The active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), is a potent regulator of innate and adaptive immunity, but its immune effects during pregnancy remain poorly understood. ...Transcriptomic responses to 1,25(OH)2D3 were characterised in pai …
The active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), is a potent regulator of innate and adaptive immu …